Medication info
Samtoget 10/10 mg

Samtoget 10/10 mg

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›10.85mg / 1 tablet
Manufacturer / importer
삼성제약(주)
Appearance
White or off-white rectangular film-coated tablet
Packaging
30 tablets/box [10 tablets/Alu-Alu × 3]
Approval status
Active

MFDS item code 202101552 · Approved 2021.02.18 · Insurance code 642308510

Summary

Main use
Lipid improvement by reducing cholesterol in hypercholesterolemia and dyslipidemia and increasing HDL
Who uses it
Adults
Adult dosage
This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day, with a recommended initial dose of 10/10 mg or 10/20 mg per day. For patients requiring a more significant reduction in LDL cholesterol (more than 55%), an initial dose of 10/40 mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks.

Ingredients

Manufacturer
삼성제약(주)

Efficacy & effects

Lipid improvement by reducing cholesterol in hypercholesterolemia and dyslipidemia and increasing HDL

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
View approved original text

This medication helps improve blood cholesterol and lipid levels in patients with primary hypercholesterolemia and homozygous familial hypercholesterolemia. It is used as an adjunct to a diet to reduce total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol, while increasing high-density lipoprotein (HDL) cholesterol. Particularly, this drug provides additional efficacy in cases where other treatments are ineffective or in high-risk patients. It is essential to identify underlying causes of dyslipidemia due to other health conditions or medications before treatment, and it should be used alongside a proper diet. Furthermore, monitoring treatment effects through appropriate blood lipid tests helps improve vascular health in patients at high risk of cardiovascular diseases. This drug is effectively used to reduce the risk of atherosclerotic vascular disease associated with hypercholesterolemia.

Dosage and Administration

Adult dosage

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day, with a recommended initial dose of 10/10 mg or 10/20 mg per day. For patients requiring a more significant reduction in LDL cholesterol (more than 55%), an initial dose of 10/40 mg per day is recommended. After starting treatment or adjusting the dose, lipid levels should be checked at intervals of more than 2 weeks.

Precautions

This medication carries a risk of muscle problems, so if severe muscle pain or weakness occurs, it is crucial to inform the doctor immediately. Patients with poor kidney function or with severe infections, major surgeries, or trauma may need to temporarily discontinue this medication. This drug should not be taken if there is an allergy to any of its components, severe liver dysfunction, or muscle disorders. Pregnant women or those who may become pregnant, as well as nursing women, should not use this medication. If taking other specific medications, it is essential to consult a doctor as interactions could increase the risk of side effects. Regular liver function tests should be conducted for those with liver dysfunction, and if symptoms of liver damage appear, the medication must be stopped immediately. This drug may cause side effects such as dizziness, muscle pain, indigestion, or increased liver enzymes, so caution is needed. Elderly patients or those with histories of liver or kidney disease should be managed more carefully when using this medication. It is important to avoid excessive alcohol consumption while taking this medication, and report any muscle pain or weakness to healthcare professionals immediately. Women taking this medication should use appropriate contraception to prevent pregnancy. Caution is advised when driving or operating machinery as dizziness may occur. This drug is not recommended for children. In case of overdose, as there is no specific antidote, appropriate treatment based on symptoms should be received, and liver function and muscle enzyme levels should be monitored.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, shortness of breath, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in mouth/eyes mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory irregularities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination

Mild side effects

  • Muscle pain
  • abdominal pain
  • nausea
  • diarrhea
  • dizziness
  • joint pain
  • musculoskeletal pain
  • muscle weakness
  • fatigue
  • headache
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  • cough
  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • elevated liver enzymes
  • anemia
  • rash
  • itching
  • skin tumors
  • thrombocytopenia
  • hepatitis
  • cholestasis
  • blurred vision
  • tinnitus
  • hearing loss
  • skin rash
  • hair loss
  • dry skin
  • sweating
  • hives
  • eczema
  • seborrhea
  • gynecomastia
  • urinary tract infections
  • difficulty urinating
  • low

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture and kept at room temperature between 1°C and 30°C. Proper storage ensures the maintenance of the drug's effectiveness and safety.

Appearance and packaging

Appearance

White or off-white rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu × 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.