Lipoduo Tablet 10/20 mg (Ezetimibe, Atorvastatin Calcium Trihydrate)

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dose range is 10/10 mg to 10/80 mg daily, with an initial dose recommended at 10/10 mg or 10/20 mg per day. For patients requiring greater reductions in LDL cholesterol (more than 55%), an initial dose of 10/40 mg per day is advised. Blood lipid levels will be checked after at least two weeks following administration.

This medication may have a risk of muscle problems; if sudden muscle pain or weakness occurs, consult a doctor immediately. There is a risk of severe muscle damage leading to impaired kidney function; therefore, if there are risk factors such as acute infection, surgery, or trauma, the use of this medication should be temporarily halted. Patients allergic to any of the ingredients, with severely impaired liver function, muscle disease, pregnant or nursing women should not take this medication. Additionally, patients with certain antiviral drugs or lactose intolerance should avoid this medication. Caution is necessary when administering this medication to patients with a history of alcohol dependence or liver disease, those with impaired kidney function, the elderly, or those with hypothyroidism. Patients with a high risk of myopathy or rhabdomyolysis should be advised to undergo muscle-related tests before and during treatment. This medication may cause liver function abnormalities; therefore, regular liver function tests should be conducted before and during use, and if signs of hepatitis or jaundice occur, the medication should be stopped immediately. Pregnant or potentially pregnant women should avoid this medication, and appropriate contraceptive measures should be taken while using it. Dizziness and other symptoms may occur, necessitating caution when driving or operating machinery. There may be interactions with other drugs; therefore, if taking any other medications, inform your doctor or pharmacist. There is no specific antidote for overdose; appropriate treatment and examination according to symptoms are necessary. Safety in children or adolescents has not been established, so it is not recommended. This medication should be stored out of reach of children and should not be transferred to another container.

Serious side effects

Hives, angioedema, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), severe skin adverse reactions including erythema multiforme, jaundice, hepatitis, liver failure, severe allergic reactions, rhabdomyolysis, myopathy, myositis, immune-mediated necrotizing myopathy, kidney failure, severe edema, intracranial aneurysm, hemorrhagic stroke, confusion, seizures, palpitations, tachycardia, myocardial ischemia, congestive heart failure,

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• dizziness
• fatigue
• headache
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. The storage temperature should be maintained safely between 1 degree and 30 degrees Celsius.

Appearance

White or light yellow, biconvex, capsule-shaped film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu×3]