Zetova Tablet 10/40 mg

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dosage is 10/10 mg to 10/80 mg daily. The initial dosage recommended is 10/10 mg or 10/20 mg daily. For patients needing greater reduction in LDL-cholesterol, an initial dosage of 10/40 mg daily is recommended. After starting treatment or adjusting the dosage, lipid levels should be checked at intervals of more than 2 weeks.

This medication is used to lower blood cholesterol levels. It may affect muscles, and if severe muscle pain or weakness occurs, consult a physician immediately. Particularly in cases of severe infections, hypotension, major surgeries, or trauma where there is a risk of renal functionality impairment, temporary suspension of the medication may be necessary. Individuals with allergies to any ingredients in this medication or those with liver disease, muscle diseases, or pregnant or nursing women should not use it. Patients with specific liver diseases or persistently elevated serum liver enzyme levels should also avoid this medication. Cautious use is advised for individuals with alcoholism, impaired liver function, renal impairment, hypothyroidism, and the elderly. This medication may interact with other drugs, particularly when taken with medications that inhibit enzymes that break down drugs in the liver, which may increase the risk of muscle damage. Regular liver function tests should be performed during treatment, and a physician should be consulted if any abnormal signs appear. Pregnant women or those who may become pregnant should not take this medication and must confirm their pregnancy status if they are taking it. It is not recommended for children as safety and efficacy have not been established. In case of overdose, there is no specific antidote, so appropriate treatment and supportive therapy according to symptoms are necessary. Keep this medication out of reach of children, and it is advisable not to transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), skin rash, vascular edema, skin-mucosal syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell's syndrome), polymorphic erythema, liver abnormalities (jaundice), acute renal failure, rhabdomyolysis, severe myopathy, severe muscle weakness or ocular muscle weakness, severe allergic reactions, severe skin adverse reactions, serious neurological symptoms (intracranial aneurysm, seizures, confusion, visual disturbances.

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• headache
• dizziness
• joint pain
• joint swelling
• back pain
• neck pain

Store this medication in a tightly closed container to protect it from air and moisture. It is recommended to maintain room temperature between 1 and 30 degrees Celsius.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP pack (Alu-Alu) x3]