Medication info
Atoe Tablet 10/20 Milligrams

Atoe Tablet 10/20 Milligrams

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›21.7mg / 1 tablet
Manufacturer / importer
(주)일화
Appearance
White or near-white rectangular film-coated tablet
Packaging
30 tablets/box [(10 tablets/Alu-Alu x 3)]
Approval status
Active

MFDS item code 202101528 · Approved 2021.02.18 · Insurance code 640904200

Summary

Main use
Reduction of cholesterol in hypercholesterolemia (primary, homozygous familial) and improvement of lipids by increasing HDL.
Who uses it
Adults
Adult dosage
This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg daily, with a recommended initial dose of 10/10mg or 10/20mg daily. Patients requiring a more significant reduction in LDL cholesterol (more than 55%) are advised to start with a dose of 10/40mg daily. After starting the treatment or dose adjustment, blood lipid levels should be checked with an interval of more than 2 weeks.

Ingredients

Manufacturer
(주)일화

Efficacy & effects

Reduction of cholesterol in hypercholesterolemia (primary, homozygous familial) and improvement of lipids by increasing HDL.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
View approved original text

This medication is primarily used to manage blood cholesterol and lipid levels in patients with primary hypercholesterolemia and mixed dyslipidemia. It lowers total cholesterol, bad LDL cholesterol, apo B protein, triglycerides, and non-HDL cholesterol while increasing good HDL cholesterol. Additionally, it can be used as an adjunct or alternative therapy for patients with homozygous familial hypercholesterolemia. This drug is used in conjunction with an appropriate diet; it is essential to take it when the diet alone is insufficient. Other risk factors must be considered according to the patient's condition, and other causes of dyslipidemia should be adequately assessed and treated. In summary, this drug helps improve hypercholesterolemia and dyslipidemia and reduces the risk of cardiovascular diseases.

Dosage and Administration

Adult dosage

This medication is taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg daily, with a recommended initial dose of 10/10mg or 10/20mg daily. Patients requiring a more significant reduction in LDL cholesterol (more than 55%) are advised to start with a dose of 10/40mg daily. After starting the treatment or dose adjustment, blood lipid levels should be checked with an interval of more than 2 weeks.

Precautions

This medication is used to lower blood cholesterol levels. Before administration, it is essential to check for the risk of severe muscle diseases such as myopathy or rhabdomyolysis. If these symptoms occur, inform your doctor immediately and, if necessary, stop taking the medication. Patients with poor liver function or liver disease should not take this medication and should undergo regular liver function tests during treatment. Pregnant women or those who may become pregnant, as well as nursing mothers, should not use this drug. Women of childbearing age should use appropriate contraceptive methods. Patients with alcohol dependence, the elderly, and those with renal dysfunction should use this medication with caution and may require dosage adjustments as directed by their physician. When used in combination with other specific medications, the risk of myopathy may increase, so it is crucial to consult with a physician or pharmacist. During treatment, symptoms such as muscle pain, muscle weakness, malaise, and fever may occur; therefore, it is important to monitor these carefully. Dizziness or cough may occur, so caution should be exercised when driving or operating machinery. In the event of an overdose, there is no specific antidote, so it is important to visit a medical institution immediately for appropriate treatment and evaluation. Safety and efficacy have not been established in children or minors, so it is not recommended for them. Store this medication out of reach of children, and be cautious not to transfer it to another container, as this may affect its quality.

Side effects and when to seek care immediately

Serious side effects

Rash, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, difficulty breathing or shortness of breath, asthma attack, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden severe headache, thunderclap headache, seizure, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

  • Muscle pain
  • abdominal pain
  • dizziness
  • headache
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
  • nosebleed
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  • cough
  • fatigue
  • malaise
  • chest pain
  • chest discomfort
  • edema
  • weakness
  • fever
  • insomnia
  • nightmares
  • sensory disturbances
  • taste disturbances
  • memory loss
  • rash
  • skin rash
  • itching
  • hair loss
  • thrombocytopenia
  • hepatitis
  • blurred vision
  • tinnitus
  • dry skin
  • sweating
  • acne
  • increased blood pressure
  • anemia
  • tachycardia
  • dizziness

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it is best to store the medication at room temperature, between 1 to 30 degrees Celsius, avoiding excessively hot or cold conditions.

Appearance and packaging

Appearance

White or near-white rectangular film-coated tablet

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.