Atovaef Tablet 10/10 mg

Adult dosage

This medication is taken once daily without regard to meals. For primary hypercholesterolemia, the dosing range is from 10/10 mg to 10/80 mg once a day. An initial dose of 10/10 mg or 10/20 mg once a day is recommended. For patients requiring more significant reductions in LDL cholesterol, an initial dose of 10/40 mg once a day is recommended. Dosage adjustments should be made at intervals of more than 2 weeks after checking blood lipid levels.

This medication can rarely cause muscle tissue damage, leading to muscle pain or weakness; in severe cases, it can result in a serious condition called rhabdomyolysis. Due to the risk of rapid deterioration of kidney function, treatment should be discontinued immediately, and a doctor should be consulted if severe myopathy symptoms occur. Additionally, it can affect liver function, so liver function tests should be performed regularly before and during treatment. This medication should not be administered to patients with certain liver diseases or those with abnormally high liver enzyme levels. Women who are pregnant, likely to become pregnant, or breastfeeding should not take this medication. There may be interactions when taken with other medications, so any medications currently being taken should be disclosed to healthcare providers. Special caution is needed when taken with medications that affect liver function or may increase muscle toxicity. Symptoms such as dizziness, muscle pain, or abdominal pain may occur, and if these symptoms persist or worsen, a doctor should be informed. Elderly patients or those with impaired kidney function should also exercise caution when taking this medication, and thorough consultation with a healthcare provider is recommended before taking it. It is advisable to avoid alcohol consumption during the treatment, and regular blood tests and clinical monitoring are recommended.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain of mucous membranes in the mouth/eyes, difficulty in breathing or shortness of breath, asthma attack, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), generalized malaise, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

White oblong film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP x3)], 30 tablets/bottle, 100 tablets/bottle