Barodown Tablet 10/40 mg

Adult dosage

This medication is taken once a day regardless of meals. For primary hypercholesterolemia, it is administered within a dosage range of 10/10 mg to 10/80 mg daily. The recommended initial dose is 10/10 mg or 10/20 mg once daily. If a greater reduction in LDL-C is required, an initial dose of 10/40 mg is recommended. For patients with homozygous familial hypercholesterolemia, the daily dose is 10/40 mg.

This medication has been reported to cause a rare side effect called rhabdomyolysis, which can lead to severe muscle damage. If severe muscle pain or muscle weakness symptoms arise, consult a doctor immediately. Particularly, in cases with risk factors such as severe infection, hypotension, post-major surgery, trauma, metabolic disorders, endocrine issues, electrolyte imbalance, or uncontrolled seizures, the use of this medication should be temporarily suspended or discontinued. Patients with allergies to the active ingredients or components of this medication, active liver disease, unexplained elevation of liver enzymes, those with muscle diseases, pregnant or breastfeeding women, and patients taking certain antiviral drugs should not take this medication. Alcoholics, patients with moderate to severe liver dysfunction, renal impairment, hypothyroidism, a history of genetic muscle disease, elderly individuals, and those at high risk for myopathy should use this medication with caution. This medication contains Tartrazine (Yellow No. 4), so those allergic to this ingredient should take caution. During treatment, symptoms such as muscle pain, fatigue, and muscle pain with fever may occur, and if these symptoms arise, inform healthcare professionals immediately. Liver function abnormalities may occur, so liver function tests should be performed regularly before and during administration, and if symptoms such as nausea, vomiting, fatigue, or jaundice appear, administration should be discontinued. This medication may interact with many drugs, so if taking other medications, it is essential to inform the healthcare provider, especially with caution when combined with CYP3A4 inhibitors, cyclosporine, fibrate-class drugs, certain antibiotics, and antiviral agents. Pregnant women or women who may become pregnant should not take this medication, and women of childbearing age should use appropriate contraceptive methods while taking this medication. Breastfeeding women should also avoid taking this medication for safety. Safety and effectiveness have not been established for children, and it is not recommended. Elderly individuals are at high risk of myopathy, so caution is necessary when taking this medication, but dose adjustment is generally not required. Patients with severe renal or liver dysfunction should use this medication cautiously and may require dosage adjustment. There are no specific antidotes for overdose, so treatment should be symptomatic along with monitoring liver function and muscle enzyme levels. This medication should be stored out of the reach of children and should not be transferred to another container. Dizziness may occur during treatment, so caution should be exercised when driving or operating machinery.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash accompanied by high fever, blistering, skin peeling, pain in oral or ocular mucosa, shortness of breath or dyspnea, asthma attacks, cough with fever accompanying respiratory discomfort, jaundice (yellowing of skin or eyes), profound lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

• Muscle pain
• abdominal pain
• dizziness
• nausea
• diarrhea
• joint pain
• musculoskeletal pain
• cough
• fatigue
• headache

This medication should be stored in a tightly closed container to prevent air or moisture from entering and is best kept at room temperature between 1 and 30 degrees Celsius.

Appearance

White, oval film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3], 30 tablets/bottle, 100 tablets/bottle