Medication info
Atorva Tablet 10/10 mg

Atorva Tablet 10/10 mg

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›10.85mg / 1 tablet
Manufacturer / importer
(주)한국파비스제약
Appearance
White or off-white oblong film-coated tablet
Packaging
30 tablets/box [10 tablets/Alu-Alu*3]
Approval status
Active

MFDS item code 202101494 · Approved 2021.02.18 · Insurance code 621804250

Summary

Main use
Reduction of cholesterol in hypercholesterolemia (primary, homozygous familial) and dyslipidemia, and suppression of cardiovascular disease risk by increasing HDL.
Who uses it
Adults
Adult dosage
This medication is administered once daily regardless of meals. For primary hypercholesterolemia, a dosage of 10/10 mg to 10/80 mg daily is used, with an initial dose recommended at 10/10 mg or 10/20 mg once daily. In cases where a significant reduction in LDL cholesterol is required, an initial dose of 10/40 mg daily is recommended. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40 mg once daily or

Ingredients

Manufacturer
(주)한국파비스제약

Efficacy & effects

Reduction of cholesterol in hypercholesterolemia (primary, homozygous familial) and dyslipidemia, and suppression of cardiovascular disease risk by increasing HDL.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • hypercholesterolemia
  • dyslipidemia
View approved original text

This medication is used as an adjunct to dietary therapy for patients with primary hypercholesterolemia and mixed dyslipidemia to reduce elevated total cholesterol, LDL cholesterol, Apo B proteins, and triglycerides, while increasing HDL cholesterol. It can be administered to patients with homozygous familial hypercholesterolemia either in conjunction with or as an alternative to other lipid-lowering treatments. This drug has been studied for specific types of dyslipidemia and is recommended for cases where there is insufficient response to appropriate dietary adjustments and non-pharmacological treatment. It is important to identify and treat other secondary causes prior to administration, and to manage the condition with regular lipid testing during treatment. This drug helps reduce risks associated with hypercholesterolemia and related cardiovascular diseases and aids in controlling lipid levels.

Dosage and Administration

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, a dosage of 10/10 mg to 10/80 mg daily is used, with an initial dose recommended at 10/10 mg or 10/20 mg once daily. In cases where a significant reduction in LDL cholesterol is required, an initial dose of 10/40 mg daily is recommended. The recommended dosage for patients with homozygous familial hypercholesterolemia is 10/40 mg once daily or

Precautions

This medication is used to lower blood cholesterol levels. When taking this medication, there is a risk of abnormalities in the muscles, so if symptoms of muscle pain or weakness develop, you must immediately inform a physician and undergo examination. Particularly serious myopathy or rhabdomyolysis may occur, which can lead to rapid deterioration of kidney function, so caution is required. Patients with poor liver function or liver disease should not take this medication, and regular liver function tests should be performed. Women who are pregnant, may become pregnant, or are breastfeeding should not take this medication. Patients with alcohol dependence, a history of kidney disease, and the elderly should be cautious while taking this medication; dose adjustments and careful monitoring are necessary if required. This medication has many interactions with other drugs, so be sure to inform your physician or pharmacist of any other medications you are taking. Attention is especially required when taking it with specific antibiotics, antiviral agents, immunosuppressants, and fibrate drugs, as this can increase the likelihood of muscle adverse reactions. Dizziness or fatigue may occur during the use of this medication, requiring caution when driving or operating machinery. In case of overdose, there is no specific antidote, so appropriate treatment should be received according to symptoms, and liver function and muscle status should be monitored. The safety and efficacy of this medication have not been established in children, thus it is not recommended. This medication should strictly be taken according to a physician’s prescription and instructions, and if any adverse symptoms occur, one should immediately consult medical personnel.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue throughout the body, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual abnormalities, paralysis, urination

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
  • hyperkalemia
Show 27 more
  • bronchitis
  • sinusitis
  • flushing
  • diarrhea
  • constipation
  • fatigue
  • chest pain
  • malaise
  • lethargy
  • fever
  • vomiting
  • belching
  • pancreatitis
  • pharyngeal/laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • sensory disturbances
  • sensory loss
  • taste disturbances
  • amnesia
  • peripheral neuropathy
  • itching
  • rash
  • hair loss
  • thrombocytopenia
  • hepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is best to maintain storage temperatures between 1 and 30 degrees Celsius. Storing it this way helps maintain the efficacy and safety of the medication.

Appearance and packaging

Appearance

White or off-white oblong film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu*3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.