Medication info
Lipiget Tablets 10/40 mg

Lipiget Tablets 10/40 mg

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›43.4mg / 1 tablet
Manufacturer / importer
신일제약(주)
Appearance
White or off-white rectangular film-coated tablet
Packaging
30 tablets/box [(10 tablets/Alu-Alu x 3)]
Approval status
Active

MFDS item code 202101466 · Approved 2021.02.18 · Insurance code 653805920

Summary

Main use
Lipid-regulating effect through cholesterol reduction and HDL increase in hypercholesterolemia (primary, homozygous familial) and dyslipidemia.
Who uses it
Adults
Adult dosage
This medication is administered once daily, without regard to meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day, with an initial dose of either 10/10 mg or 10/20 mg recommended. For patients requiring a greater reduction in LDL cholesterol, an initial dose of 10/40 mg once daily is recommended. After starting treatment, lipid levels should be checked at intervals of at least two weeks to adjust the dosage accordingly.

Ingredients

Manufacturer
신일제약(주)

Efficacy & effects

Lipid-regulating effect through cholesterol reduction and HDL increase in hypercholesterolemia (primary, homozygous familial) and dyslipidemia.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
View approved original text

This medication is used as an adjunct to dietary therapy to lower elevated total cholesterol, LDL cholesterol, Apo B, triglycerides, and non-HDL cholesterol levels, and to increase HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia. It may also be administered as an adjunctive treatment in patients with homozygous familial hypercholesterolemia when other lipid-lowering therapies are ineffective. This medication is recommended for use when considering multiple risk factors in the treatment of dyslipidemia and when there is inadequate response to dietary and non-pharmacological measures. Before use, it is essential to identify and treat secondary causes such as diabetes and hypothyroidism, and lipid testing should be conducted. Thus, this medication helps reduce the risk of vascular diseases due to hypercholesterolemia and improves effective lipid control along with dietary therapy.

Dosage and Administration

Adult dosage

This medication is administered once daily, without regard to meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day, with an initial dose of either 10/10 mg or 10/20 mg recommended. For patients requiring a greater reduction in LDL cholesterol, an initial dose of 10/40 mg once daily is recommended. After starting treatment, lipid levels should be checked at intervals of at least two weeks to adjust the dosage accordingly.

Precautions

This medication helps lower blood cholesterol levels and reduce the risk of cardiovascular diseases. However, it can occasionally cause severe damage to the muscles, which can lead to a rapid decline in kidney function; therefore, caution is necessary. If serious muscle pain or weakness occurs, it is essential to inform a doctor immediately, and it may be necessary to temporarily suspend or discontinue this medication if such symptoms develop. Patients with impaired liver function or liver disease, muscle disorders, pregnant women or women who may become pregnant, and breastfeeding women should not use this medication. Alcoholics or patients with a history of liver function issues, impaired kidney function, hypothyroidism, and elderly patients require special attention when taking this medication. The risk of muscle damage may increase when taken with other specific medications, so any current medications should be disclosed to a doctor or pharmacist. Regular monitoring of liver function tests is necessary; if symptoms of liver dysfunction (e.g., nausea, vomiting, fatigue) occur, treatment should be stopped immediately, and a doctor should be consulted. Additionally, this medication may be harmful to the fetus during pregnancy, so women of childbearing potential should use appropriate contraceptive methods while taking it. Since side effects such as dizziness or muscle pain may occur, caution is advised when driving or operating machinery. Safety in children or adolescents has not been established, so it is not recommended. In case of overdose, there is no specific antidote available, so treatment and supportive care according to symptoms should be administered, and liver function and muscle conditions should be monitored.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, mucosal pain in mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • constipation
  • diarrhea
  • joint pain
  • muscle weakness
Show 27 more
  • musculoskeletal pain
  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • fatigue
  • headache
  • vomiting
  • indigestion
  • pharyngitis
  • sinusitis
  • upper respiratory infection
  • low back pain
  • muscle cramps
  • urticarial
  • skin rash
  • itching
  • hair loss
  • thrombocytopenia
  • hepatitis
  • blurred vision
  • tinnitus
  • skin tumors
  • sweating
  • eczema
  • seborrhea
  • skin ulcers

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is essential to maintain storage at room temperature between 1 degree and 30 degrees Celsius. This helps ensure the medication remains effective and safe to use.

Appearance and packaging

Appearance

White or off-white rectangular film-coated tablet

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.