Medication info
Ato Ajet Tablet 10/20 Milligrams

Ato Ajet Tablet 10/20 Milligrams

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Trihydrate›21.7mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
제일헬스사이언스(주)
Appearance
White to off-white, double convex, oval film-coated tablet
Packaging
30 tablets/box[(10 tablets/PTP x 3)]
Approval status
Active

MFDS item code 202101436 · Approved 2021.02.18

Summary

Main use
Improvement of lipids by reducing cholesterol and increasing HDL in hypercholesterolemia and dyslipidemia.
Who uses it
Adults
Adult dosage
This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, an initial dose of 10/10 mg or 10/20 mg once daily is recommended. For patients requiring a greater reduction (more than 55%) in LDL-cholesterol, an initial dose of 10/40 mg once daily is recommended. After initiating treatment or adjusting the dose, blood lipid levels should be monitored at intervals of at least 2 weeks.

Ingredients

Manufacturer
제일헬스사이언스(주)

Efficacy & effects

Improvement of lipids by reducing cholesterol and increasing HDL in hypercholesterolemia and dyslipidemia.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
View approved original text

This medication is used to improve blood cholesterol and related lipid levels in patients with primary hypercholesterolemia and mixed dyslipidemia. In particular, it effectively lowers levels of total cholesterol, LDL-cholesterol, Apo B protein, triglycerides, and non-HDL-cholesterol, while increasing HDL-cholesterol. This medication can also be used as an adjunctive treatment for patients with homozygous familial hypercholesterolemia and serves as an alternative therapy when other lipid-lowering treatments are not effective. It is important to combine use with appropriate dietary measures and non-pharmacological actions, allowing for maximum efficacy by identifying and treating secondary causes of dyslipidemia. This medication helps reduce the risk of cardiovascular disease and improve blood lipid levels.

Dosage and Administration

Adult dosage

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, an initial dose of 10/10 mg or 10/20 mg once daily is recommended. For patients requiring a greater reduction (more than 55%) in LDL-cholesterol, an initial dose of 10/40 mg once daily is recommended. After initiating treatment or adjusting the dose, blood lipid levels should be monitored at intervals of at least 2 weeks.

Precautions

This medication has a risk of serious muscle problems, so if sudden muscle pain or weakness occurs, consult a doctor immediately. In cases of severe infection, hypotension, major surgery or trauma, or electrolyte imbalances that may worsen kidney function, it may be necessary to temporarily discontinue this medication. Individuals allergic to the active ingredients or components of this medication, those with severe liver dysfunction, muscle diseases, pregnant or potentially pregnant women, and individuals who are breastfeeding should not take this medication. Additionally, those undergoing treatment with certain antiviral drugs or individuals with lactose intolerance should not use this medication. People with a history of alcohol dependency or liver disease, severe liver dysfunction, poor kidney function, hypothyroidism, and elderly individuals, who may be at higher risk for muscle issues, should use this medication with caution. Be cautious if taking fibrate-class medication concurrently. This medication may cause side effects such as muscle pain, abdominal pain, and elevated liver enzymes; in severe cases, it may lead to muscle destruction, so notify a doctor if symptoms occur. There may be liver function abnormalities, so liver function tests should be conducted before starting treatment and during treatment. Pregnant or breastfeeding women should not take this medication as it can be harmful to the fetus or infant, and women of childbearing age should use appropriate contraception while taking it. This medication is not recommended for children as its safety has not been established. Elderly patients should pay particular attention due to the higher risk of muscle problems, and patients with poor liver or kidney function should take it according to a doctor's instructions. This medication has many drug interactions, so dose adjustments or caution may be needed according to the medications being taken, so inform healthcare professionals about all medications being used. In the case of overdose, there is no specific antidote, so symptomatic treatment and liver function and muscle enzyme tests should be conducted. Finally, keep this medication out of reach of children and do not transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Muscle pain
  • abdominal pain
  • elevated liver enzymes
  • dizziness
  • cough
  • nausea
  • diarrhea
  • joint pain
  • muscle weakness
  • musculoskeletal pain
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  • hyperkalemia
  • bronchitis
  • sinusitis
  • flushing
  • headache
  • fatigue
  • constipation
  • vomiting
  • muscle cramps
  • muscle fatigue
  • itching
  • rash
  • hair loss
  • thrombocytopenia
  • hepatitis
  • cholestasis
  • blurred vision
  • tinnitus
  • hearing loss
  • gynecomastia
  • low back pain
  • anemia
  • hernia
  • hyperglycemia
  • hypoglycemia
  • loss of appetite
  • vomiting
  • pancreatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering and should be kept in a cool place below 30 degrees Celsius. This helps maintain the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

White to off-white, double convex, oval film-coated tablet

Package unit

30 tablets/box[(10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.