Ezetimibe and Atorvastatin Calcium Tablet 10/20 mg

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, an initial dose of 10/10 mg or 10/20 mg daily is recommended. For patients requiring greater reductions in LDL cholesterol, an initial dose of 10/40 mg daily is recommended. Dose adjustments should be made after checking blood lipid levels at intervals of more than 2 weeks. For homozygous familial hypercholesterolemia, the recommended dose is

This medication may pose serious risks to muscles, so if symptoms such as muscle pain or weakness occur, inform your doctor immediately. Particularly in cases of impaired kidney function, severe infections, major surgeries, or trauma that stress the kidneys, this medication should be temporarily stopped or discontinued. Do not use if allergic to any components of this medication or if there are liver problems or muscle diseases. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication. Individuals with alcoholism or a history of liver disease should use this medication with caution. Additionally, caution is advised for those with reduced kidney function, hypothyroidism, a family history of myopathy, and elderly patients over 70 years old. The risk of muscle issues increases when taking fibrate-class medications concurrently, so use with caution. Routine liver function tests are required during the use of this medication; if liver function deteriorates, discontinue use. Severe liver issues such as hepatitis or jaundice may rarely occur, so if symptoms such as nausea, vomiting, or fatigue arise, inform your doctor immediately. This medication may raise blood glucose levels, so those at risk for diabetes must closely monitor their blood sugar levels. Furthermore, this medication can interact with various other drugs, so inform your doctor or pharmacist if you are taking other medications. Particular caution is needed when taking it with certain antibiotics, antivirals, immunosuppressants, analgesics, and anticoagulants. Women of childbearing age should use appropriate contraception during this medication, and if they are planning to conceive or are pregnant, they should avoid using it. Dizziness or fatigue may occur; therefore, caution is needed when driving or operating machinery. This medication is not recommended for children, as its safety and efficacy have not been established. In the case of overdose, there are no specific antidotes; management should be symptomatic, monitoring liver function and muscle condition. Keep this medication out of reach of children, and avoid transferring it to other containers.

Serious side effects

Hives, severe swelling (edema), chest discomfort, breathing difficulties, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination problems

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• joint pain
• musculoskeletal pain
• hyperkalemia
• bronchitis
• sinusitis
• flushing

This medication should be stored in a tightly sealed container to prevent air or moisture exposure, ideally at room temperature between 1 degree and 30 degrees Celsius. Storing it this way helps maintain its efficacy over time.

Appearance

White or off-white oblong film-coated tablet

Package unit

30 tablets/box [(10 tablets/Alu-Alu x 3)]