Lipitor Plus Tablet 10/40 mg

Adult dosage

This drug is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg daily, with an initial dose of 10/10 mg or 10/20 mg recommended. For patients requiring greater reduction in LDL-cholesterol (more than 55%), an initial dose of 10/40 mg daily is recommended. After initiation of treatment or adjustment of dosage, lipid levels should be checked at intervals of more than 2 weeks.

This drug may cause abnormal reactions in muscles; if symptoms like muscle pain or weakness occur, inform your doctor immediately. Rhabdomyolysis, a severe muscle injury, has been reported rarely. If risk factors such as kidney impairment, severe infection, hypotension, or post-major surgery are present, treatment should be discontinued or paused. This drug may affect liver function, so regular liver function tests should be conducted before and during treatment. If liver damage symptoms appear, consult your doctor immediately. Patients with liver disease or persistent unexplained elevated liver enzymes should not use this drug. Co-administration with certain other medications may increase the risk of muscle abnormal reactions; inform your doctor or pharmacist if you are taking other medicines. Women who are pregnant or may become pregnant, and nursing mothers should not take this medicine, and women of childbearing age should use appropriate contraception during treatment. Patients with a history of excessive alcohol intake or liver disease, the elderly, and those with impaired kidney function should use this drug with caution and require regular check-ups. Dizziness or drowsiness may occur, so caution is needed when driving or operating machinery. Safety in children has not been established, so it is not recommended. There is no specific antidote for overdose; appropriate treatment and monitoring of liver function and muscle-related tests should be conducted according to symptoms.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, peeling skin, mucosal pain in the mouth/eyes, difficulty breathing or dyspnea, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme fatigue throughout the body, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination.

Mild side effects

• Muscle pain
• abdominal pain
• increased liver enzymes
• dizziness
• cough
• nausea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia

This drug may be sensitive to air or moisture, so it should be stored in a tightly closed container. It is advisable to maintain storage temperatures between 1 and 30 degrees Celsius. By storing it this way, the effectiveness of the drug can be maintained for a longer period.

Appearance

White to off-white, capsule-shaped, film-coated tablet with a biconvex appearance, engraved with 'JI 40' on one side.

Package unit

30 tablets/PTP [30 tablets (10 tablets/PTP x 3)], 30 tablets/bottle, 90 tablets/bottle