Medication info
Jetstan Tablet 10/10 mg

Jetstan Tablet 10/10 mg

Prescription medicationTablet
Ingredient · strength
Ezetimibe›10mg / 1 tabletAtorvastatin Calcium Trihydrate›10.85mg / 1 tablet
Manufacturer / importer
(주)동구바이오제약
Appearance
White or whitish oblong film-coated tablet
Packaging
30 tablets/box [10 tablets/Alu-Alu x 3]
Approval status
Active

MFDS item code 202101389 · Approved 2021.02.18 · Insurance code 657308490

Summary

Main use
Improvement of lipids by reducing cholesterol in hypercholesterolemia (primary, homozygous familial) and dyslipidemia, and increasing HDL.
Who uses it
Adults
Adult dosage
This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dosing range is from 10/10mg to 10/80mg daily. The recommended starting dose is 10/10mg or 10/20mg daily. Patients requiring more significant reduction in LDL cholesterol should start with a dose of 10/40mg daily as the initial dose. Dosing adjustments should be made after checking blood lipid levels at intervals of more than 2 weeks.

Ingredients

Manufacturer
(주)동구바이오제약

Efficacy & effects

Improvement of lipids by reducing cholesterol in hypercholesterolemia (primary, homozygous familial) and dyslipidemia, and increasing HDL.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • homozygous familial hypercholesterolemia
  • dyslipidemia
  • increased risk of atherosclerotic vascular disease due to hypercholesterolemia.
View approved original text

This medication helps lower total cholesterol, LDL cholesterol, apo B, triglycerides, and non-HDL cholesterol levels while increasing HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia. It can be used as an adjunct to other lipid-lowering therapies in patients with homozygous familial hypercholesterolemia or can be used alone if other treatments are ineffective. This medication is to be used in conjunction with dietary changes and is applied when there is insufficient response to non-pharmacological treatments. Prior to treatment, secondary causes such as diabetes and hypothyroidism should be identified and addressed as necessary, and it is important to confirm accurate lipid levels. It helps effectively improve total cholesterol and LDL cholesterol levels, thus reducing the risk of cardiovascular diseases.

Dosage and Administration

Adult dosage

This medication is administered once daily regardless of meals. For primary hypercholesterolemia, the dosing range is from 10/10mg to 10/80mg daily. The recommended starting dose is 10/10mg or 10/20mg daily. Patients requiring more significant reduction in LDL cholesterol should start with a dose of 10/40mg daily as the initial dose. Dosing adjustments should be made after checking blood lipid levels at intervals of more than 2 weeks.

Precautions

This medication has been reported to cause a rare side effect called rhabdomyolysis, which can result in serious muscle damage. Therefore, if symptoms of severe muscle pain or muscle weakness occur, it is important to consult a physician immediately. Additionally, this medication should not be administered to individuals with known allergies to the active ingredients or components, patients with active liver disease, individuals with muscle diseases, women who are pregnant or may become pregnant, nursing mothers, and patients taking certain other medications. Patients with alcohol dependence, impaired liver function, decreased kidney function, hypothyroidism, and the elderly should use this medication with caution, particularly when combined with other drugs that may increase the risk of muscle disease. During treatment, liver function and muscle condition should be regularly monitored; if symptoms of impaired liver function, muscle pain, fatigue, or fever occur, medical personnel should be notified immediately. Women who are pregnant or nursing should avoid taking this medication, and women of childbearing age should use appropriate contraception while on this medication. The safety and efficacy in children have not been established, hence it is not recommended for use in this age group; for the elderly, caution is needed due to the risk of myopathy. This medication may interact with other drugs; therefore, it is essential to inform healthcare professionals about any other medications being taken, especially when combined with medications that affect liver metabolism, as careful dose adjustments and monitoring are necessary. In case of overdose, there is no specific antidote available, and treatment should be symptomatic and supportive, with monitoring of liver function and muscle enzyme levels. This medication should be stored out of reach of children and should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, severe rash accompanied by high fever, blisters, peeling skin, pain in mouth/eye mucous membranes, skin and mucous membrane syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), erythema multiforme, severe skin reactions (SCARs), shortness of breath or difficulty breathing, asthma attacks, cough with accompanying fever and respiratory abnormalities, skin or

Mild side effects

  • Muscle pain
  • abdominal pain
  • dizziness
  • headache
  • nausea
  • fatigue
  • malaise
  • chest pain
  • swelling
  • musculoskeletal pain
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  • joint pain
  • low back pain
  • hyperkalemia
  • pharyngitis
  • sinusitis
  • flushing
  • diarrhea
  • vomiting
  • constipation
  • dyspepsia
  • muscle weakness
  • muscle cramps
  • muscle fatigue
  • hair loss
  • itching
  • skin rash
  • hives
  • thrombocytopenia
  • blood and lymphatic system disorders
  • anemia
  • allergic reactions
  • liver function abnormalities
  • hepatitis
  • cholestasis
  • blurred vision

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture. It is important to maintain storage temperatures between 1 and 30 degrees Celsius.

Appearance and packaging

Appearance

White or whitish oblong film-coated tablet

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.