Atorvastatin Calcium/Ezetimibe Tablet 10/40 mg

Adult dosage

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10 mg to 10/80 mg per day, with a recommended starting dose of 10/10 mg or 10/20 mg per day. For patients requiring more significant reduction in LDL cholesterol (by over 55%), a starting dose of 10/40 mg per day is recommended. After initiating treatment or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks.

This medication may cause rhabdomyolysis, which is a serious side effect associated with specific muscle diseases. This side effect can lead to muscle destruction and complications with kidney function, so if severe muscle pain or weakness occurs, consult a doctor immediately. This medication should not be administered to patients with allergies to its components or those with severe liver impairment, people with muscle diseases, pregnant or nursing women, or patients taking certain antiviral agents. Patients with a history of alcohol addiction or liver disease, severe liver dysfunction, poor kidney function, hypothyroidism, elderly patients, and others should be especially cautious when using this drug. During the course of treatment with this drug, regular liver function tests and muscle-related tests should be performed, and any symptoms of liver dysfunction or muscle pain or weakness should be reported to a doctor immediately. This drug has many drug interactions, so any other medications being taken should be disclosed to a doctor or pharmacist; caution is particularly needed when combined with certain antibiotics, antiviral agents, immunosuppressants, or fibrate medications. Women of childbearing potential should use appropriate contraception while taking this drug, and if pregnancy is confirmed, the medication should be stopped immediately. Furthermore, nursing mothers are advised to avoid taking this drug. Caution should be taken during driving or operating machinery as symptoms such as dizziness may occur. Safety in children has not been established, therefore it is generally not recommended. In case of overdose, there is no specific antidote, so treatment should be symptomatic and supportive, and the condition should be monitored through liver function and muscle-related tests. This drug should be kept out of the reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, cough with fever and respiratory distress, jaundice (yellowing of skin or eyes), extreme drowsiness, sudden and severe headaches, lightning headache, seizures, confusion, vision disturbances, paralysis, urinary retention

Mild side effects

• Muscle pain
• abdominal pain
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain
• hyperkalemia
• bronchitis
• sinusitis

This medication should be stored in a closed container to protect it from air and moisture. It is best to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature.

Appearance

White, double-convex, rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]