Atorvastatin Calcium Trihydrate / Ezetimibe Tablets 10/20 mg

Adult dosage

This medication is administered once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is from 10/10 mg to 10/80 mg per day. An initial dose of 10/10 mg or 10/20 mg per day is recommended. For patients requiring more significant reduction in LDL cholesterol (more than 55%), an initial dose of 10/40 mg per day is recommended. After administration or adjustment of dosage, liver function tests should be performed after at least 2 weeks.

This medication is used to lower blood cholesterol levels. Symptoms such as muscle pain or weakness may occur while taking this medication, and if these symptoms are severe or accompanied by fever or malaise, immediate consultation with a physician is required. Serious muscle-related problems can also affect kidney function, so caution is necessary. Therefore, during acute infections, hypotension, after major surgeries, trauma, or severe metabolic disorders, this medication may be temporarily suspended. Individuals with impaired liver function or liver disease should not take this medication and regular liver function tests should be conducted before and during treatment. If this medication is taken in conjunction with certain drugs, the risk of muscle-related side effects may increase, so if other medications are being taken, consultation with a physician or pharmacist is mandatory. Pregnant women or women who could become pregnant, as well as breastfeeding women, should not take this medication, and women of childbearing age must use appropriate contraception while on this medication. Additionally, this medication has not been established as safe and effective for children, thus it is not recommended. Elderly individuals are at higher risk for myopathy, so caution is required during use, but no special dose adjustments are necessary. In the case of overdose, there are no specific antidotes, so treatment should be symptomatic, monitoring liver function and muscle condition. This medication should be stored out of the reach of children and transferring to other containers should be avoided. Caution is required when driving or operating machinery as dizziness may occur.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, lightning-like headaches, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly closed container to prevent exposure to air or moisture and should be kept at room temperature between 1 and 30 degrees Celsius.

Appearance

White, biconvex, rectangular film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP x3]