Sitagliptin 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken irrespective of meals. For patients with renal impairment, dosage adjustment may be required based on kidney function. - Mild renal impairment (eGFR 60 or above to <90): No dosage adjustment necessary - Moderate renal impairment (eGFR 45 or above to <60): No dosage adjustment necessary - Moderate renal impairment (

This medication can rarely cause severe allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, use should be discontinued immediately and medical consultation should be sought. Additionally, serious adverse reactions such as pancreatitis, which is inflammation of the pancreas, have been reported; if symptoms such as abdominal pain, vomiting, or nausea occur, medical personnel should be notified immediately. Patients with type 1 diabetes or those who are hypersensitive to this medication should not use it, and those with impaired kidney function should take caution and adjust the dosage accordingly. When using this medication, hypoglycemic symptoms may occur, so especially when taken with insulin or sulfonylureas, blood sugar levels should be monitored frequently, and attention should be paid to hypoglycemic symptoms. Mild adverse reactions such as headache, upper respiratory tract infection, and nasopharyngitis may occur during treatment, and if severe joint pain or blistering skin symptoms develop, notify a doctor immediately. Women who are pregnant or breastfeeding are advised to avoid using this medication, and the safety in children and adolescents under 18 years old has not been established. Elderly patients may have impaired kidney function, so periodic kidney function tests should be performed before and after taking this medication, and if an overdose occurs, immediate visit to a medical facility for appropriate treatment is required. When used in combination with other drugs, potential interaction should be considered, so consultation with a doctor or pharmacist before use is mandatory.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe allergic reactions, exfoliative skin disorders, Stevens-Johnson syndrome, severe skin adverse reactions, acute pancreatitis, acute renal failure, difficulty breathing, severe edema, severe joint pain with disability, blistering pemphigoid, rhabdomyolysis, liver abnormalities (elevated liver enzymes), cardiac arrest

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• pruritus

Store this medication in a sealed container to prevent air from entering. It is best to store at room temperature between 1 to 30 degrees Celsius. This will help maintain the medication's effectiveness for a longer period.

Appearance

Film-coated tablets that are round, biconvex, and light brown in color

Package unit

PTP - 28 tablets/box [(14 tablets/PTP×2)]