Sitagliptin 25 mg Tablets (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. In patients with moderate renal impairment (glomerular filtration rate [eGFR] ≥ 30 mL/min/1.73 m2 and < 45 mL/min/1.73 m2), the dosage is 50 mg once daily. In patients with severe renal impairment (glomerular filtration rate [eGFR] ≥ 15 mL/min/1.73 m2 and < 30 m...

This medication may cause severe hypersensitivity reactions after administration; if allergic symptoms are suspected, discontinue use immediately and consult a healthcare professional. Symptoms of pancreatitis may occur during the use of this medication; therefore, careful observation is required for signs such as abdominal pain or vomiting, and if suspected, discontinue the medication and inform your doctor. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in patients with allergies to this medication or its components. Patients with decreased kidney function may have slower excretion of this medication; therefore, adjustments in dosage are necessary, and regular kidney function testing is important. When used with other diabetes medications that may cause hypoglycemia, there may be an increased risk of hypoglycemia, so symptoms should be carefully monitored and dosage adjusted if necessary. Severe joint pain or the appearance of blisters may occur, and if such symptoms arise, immediate consultation with a doctor is required, and the medication may need to be discontinued if necessary. It is advisable for pregnant or lactating women not to use this medication, and safety in children or adolescents under 18 years of age has not been established. Elderly patients may have a risk of decreased kidney function, so kidney function should be routinely monitored before and after administration. In the case of overdose, general emergency treatment is performed, and if necessary, some of the medication can be removed through dialysis. No significant interactions with other medications have been reported when this medication is used in combination, but it is safe to consult healthcare professionals when used in combination with certain medications.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe allergic reactions, including Stevens-Johnson syndrome and exfoliative skin diseases, severe rash with fever, blisters, skin peeling, oral/ocular mucosal pain, acute pancreatitis, difficulty breathing, severe skin adverse reactions, respiratory issues, acute renal failure, liver abnormalities due to increased liver enzymes (jaundice), severe swelling, severe joint pain accompanied by disability, blister-like pemphigoid

Mild side effects

• Headache
• upper respiratory tract infection
• nasopharyngitis
• diarrhea
• nausea
• dyspepsia
• dizziness
• constipation
• vomiting
• myalgia

This medication should be stored in a tightly closed container to prevent air or moisture from entering. The storage temperature should be maintained between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness and safety over time.

Appearance

Pink, round, biconvex film-coated tablets

Package unit

PTP - 28 tablets/box [(14 tablets/PTP×2)]