Janumet 50 mg (Sitagliptin Hydrochloride Hydrate)

Adult dosage

For adults, this medication is administered once daily at a dose of 100 mg, with a maximum daily dosage of 100 mg. It can be taken regardless of meals. Dosage adjustments in patients with renal impairment: - For mild and moderate renal impairment (eGFR 45 to less than 90), no dosage adjustment is necessary. - For moderate renal impairment (eGFR 30 to less than 45), administer 50 mg once daily. - For severe renal impairment and

This medication may cause serious allergic reactions in some patients. If symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a healthcare professional. There is a risk of pancreatitis, which is inflammation of the pancreas, while taking this medication. Therefore, symptoms such as abdominal pain, vomiting, or loss of appetite should be closely monitored, and a doctor should be consulted. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication. Patients who have allergies to this medication or any of its components should also avoid it. Patients with impaired kidney function may experience delayed excretion of this medication, thus the dosage should be adjusted or taken according to a physician's instructions. This medication may cause hypoglycemic symptoms when used alone or in combination with other diabetes medications, so blood glucose levels should be checked periodically, and attention should be paid to hypoglycemic symptoms. While taking this medication, side effects such as upper respiratory infections, nasopharyngitis, headache, diarrhea, and nausea may occur, and if symptoms are severe, medical consultation is advised. Particularly when taken with insulin or sulfonylureas, which can cause hypoglycemia, there is a heightened risk of low blood sugar requiring potential dosage adjustments. If joint pain or blisters on the skin develop while taking this medication, notify a physician immediately for appropriate treatment. Women who are pregnant or breastfeeding should avoid this medication as its safety has not been established. Elderly patients may experience diminished kidney function; regular kidney function tests before and after taking this medication are recommended. In the case of overdose, general emergency measures should be enacted, and if necessary, blood dialysis can remove this medication, so immediate medical attention is required. This medication has a low potential for drug interactions; however, patients should inform healthcare providers of any specific medications they are taking.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis (chest tightness, difficulty breathing, cold sweat, pallor), rash, exfoliative skin disease (including Stevens-Johnson syndrome), acute pancreatitis, acute renal failure, severe and disabling arthralgia, bullous pemphigoid, rhabdomyolysis, liver abnormalities (increased liver enzymes, symptoms of jaundice), serious neurological symptoms (including cardiac arrest), severe edema or urinary disturbances, pneumonia, and diabetes

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• constipation
• vomiting
• muscle pain
• limb pain
• back pain
• pruritus
• thrombocytopenia

Store this medication in a tightly closed container to prevent exposure to air and moisture. It is advisable to keep the storage temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance

Light apricot-colored, round, biconvex film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP × 2]