Sitagliptin 50 mg Tablets (Sitagliptin Hydrochloride Monohydrate)

Adult dose

For monotherapy or combination therapy, administer 100 mg once daily with a maximum daily dose of 100 mg. It can be taken without regard to meals. Dosage adjustments for patients with renal impairment: - Mild renal impairment: No dosage adjustment required - Moderate renal impairment (eGFR 45-60): No dosage adjustment required - Moderate renal impairment (eGFR 30-45): 50 mg once daily - Severe renal impairment and end-stage renal disease (eGFR 1

This medication may cause severe allergic reactions; therefore, if symptoms such as skin rash or difficulty breathing occur after taking the drug, discontinue use immediately and consult a doctor. Also, during treatment with this medication, there is a risk of developing pancreatitis, which can lead to inflammation of the pancreas. If symptoms like upper abdominal pain, vomiting, or nausea occur, seek medical attention immediately. This medication is not to be used in patients with type 1 diabetes or diabetic ketoacidosis, and should be avoided in patients with allergies to the drug or its components. Patients with impaired kidney function must have their dosage adjusted, so regular kidney function tests and adherence to a physician's instructions are required. Patients should be mindful of hypoglycemia symptoms during treatment. The risk of hypoglycemia may increase when used with other hypoglycemic agents like insulin or sulfonylureas, so blood sugar levels should be monitored frequently. Side effects such as headaches, upper respiratory infections, nasopharyngitis, diarrhea, and nausea may occur; if symptoms are severe, consult a physician. It is safer for pregnant or breastfeeding women to avoid this medication, and its safety and efficacy have not been established in children or adolescents under the age of 18. Elderly patients may have impaired kidney function and should consult a doctor before taking this medication, maintaining regular kidney function evaluations. In the case of overdose, seek immediate medical attention for appropriate treatment, as this drug can be partially removed through hemodialysis. If symptoms like joint pain or blistering skin appear during treatment, inform a doctor immediately and stop taking the medication. Finally, this medication may interact with other drugs, so it's essential to inform your physician or pharmacist about any current medications being taken.

Serious side effects

• Urticaria
• severe swelling (edema)
• anaphylaxis
• angioedema
• rash
• exfoliative skin diseases
• Stevens-Johnson syndrome
• acute pancreatitis
• severe hypoglycemia
• bullous pemphigoid

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• constipation
• vomiting
• headache
• muscle pain
• limb pain
• back pain
• pruritus
• thrombocytopenia

This medication should be stored in a tightly sealed container to avoid exposure to air and is recommended to be kept at room temperature between 1 to 30 degrees Celsius. This helps maintain the drug's efficacy and safety.

Appearance

Light apricot-colored, biconvex, round film-coated tablets

Package unit

28 tablets/PTP [(14 tablets/PTP x 2)]