Medication info
Esomac 40/600 mg

Esomac 40/600 mg

Prescription medicationTablet경구
Ingredient · strength
Esomeprazole Magnesium Trihydrate›44.5mg / 1 tabletPrecipitated Calcium Carbonate›600mg / 1 tablet
Manufacturer / importer
(주)녹십자
Appearance
Pink, oval film-coated tablet
Packaging
28 tablets/box [7 tablets/PTP x 4]
Approval status
Active

MFDS item code 202101159 · Approved 2021.02.05 · Insurance code 643606050

Summary

Main use
Treatment and prevention of erosive reflux esophagitis, relief of gastroesophageal reflux disease symptoms
Who takes it
Adults
Adult dose
Take this medication on an empty stomach at least 1 hour before meals. Swallow whole with at least half a cup of water. Do not take with any beverage other than water. This medication should not be chewed or crushed. For the treatment of gastroesophageal reflux disease (GERD) and erosive reflux esophagitis: administer 40/600 mg once daily for 4 weeks. If unresolved or if symptoms persist, take for an additional 4 weeks. For esophagitis

Ingredients

Manufacturer
(주)녹십자

Efficacy & effects

Treatment and prevention of erosive reflux esophagitis, relief of gastroesophageal reflux disease symptoms

  • Gastroesophageal reflux disease
  • erosive reflux esophagitis
  • recurrence in patients with esophagitis
View approved original text

Gastroesophageal reflux disease is a condition where stomach contents reflux into the esophagus, and this medication is effective in treating erosive reflux esophagitis. It is also used for long-term maintenance therapy to prevent recurrence in patients with esophagitis. It helps alleviate symptoms of gastroesophageal reflux disease in individuals without esophagitis. This medication is utilized to improve these symptoms and conditions, enhancing the quality of life for patients.

How to take

Adult dose

Take this medication on an empty stomach at least 1 hour before meals. Swallow whole with at least half a cup of water. Do not take with any beverage other than water. This medication should not be chewed or crushed. For the treatment of gastroesophageal reflux disease (GERD) and erosive reflux esophagitis: administer 40/600 mg once daily for 4 weeks. If unresolved or if symptoms persist, take for an additional 4 weeks. For esophagitis

Precautions

This medication should not be used in certain patients. Patients who are allergic to this medication or its components or have experienced hypersensitivity reactions should not take it. Furthermore, patients currently taking certain antiviral medications, lactating women, and individuals with severe renal impairment should also avoid using this medication. Patients with genetically inherited lactose intolerance should refrain from using this drug. Patients with poor liver function, elderly patients, those with severe gastrointestinal conditions, or problems related to heart and lung function, as well as those with constipation should use this medication with caution. While taking this medication, various adverse reactions may occur, and caution is advised. Common gastrointestinal symptoms include headache, abdominal pain, diarrhea, constipation, nausea, and vomiting. Rarely, blood abnormalities, allergic reactions, liver function abnormalities, skin rashes, and muscle pain have been reported. If symptoms such as muscle pain or weakness, or increased creatine kinase levels occur, immediate consultation with healthcare professionals is necessary. Long-term use of this medication may increase the risk of bacterial growth in the stomach or certain infections, as well as an increased risk of fractures, necessitating regular check-ups. Additionally, prolonged use may lead to hypomagnesemia, so magnesium levels should be monitored regularly. There may be interactions with other medications during the use of this drug, particularly when taken with anticoagulants, antiviral drugs, anticonvulsants, or certain antibiotics, so caution is needed. Patients must inform their doctors or pharmacists about any medications they are currently taking, as dose adjustment or monitoring may be necessary. Safety information regarding this medication during pregnancy is limited, so it should be used cautiously after consulting with a doctor, and use while nursing is not advised. In cases of overdose, there is no specific antidote, and treatment will be symptomatic. It should be stored out of the reach of children. This medication acts by suppressing or neutralizing gastric acid secretion, assisting in the treatment of gastrointestinal diseases, but it is crucial to confirm the absence of serious conditions such as gastrointestinal bleeding or malignant tumors before use. The treatment period and dosage should be maintained at the minimum necessary level, with consultation from healthcare professionals if symptoms change.

Side effects and when to seek care immediately

Serious side effects

  • Hypersensitivity reactions such as urticaria, angioedema, anaphylaxis/shock.
  • Severe hypomagnesemia.
  • Hepatitis, liver failure, with or without jaundice.
  • Skin and mucous membrane reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, and drug reaction with eosinophilia and systemic symptoms (DRESS syndrome).
  • Interstitial nephritis.
  • Clostridium difficile-associated diarrhea.
  • Severe edema or urinary abnormalities.

Mild side effects

Headache, dizziness, drowsiness, insomnia, anxiety, mental confusion, depression, aggression, hallucinations, taste disturbance, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, dermatitis, itching, rash, hair loss, photosensitivity, arthralgia, myalgia, weakness, increased sweating, myasthenia, Clostridium difficile-associated diarrhea, allergic reactions, facial swelling, facial flushing, fatigue, fever, influenza.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius. Proper storage helps to preserve the medication's effectiveness for a longer duration.

Appearance and packaging

Appearance

Pink, oval film-coated tablet

Package unit

28 tablets/box [7 tablets/PTP x 4]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.