Medication info
Bukwang Methimazole Tablet 2.5 mg

Bukwang Methimazole Tablet 2.5 mg

Prescription medicationTablet
Ingredient · strength
Methimazole›2.5mg / 1 tablet
Manufacturer / importer
Bukwang Pharmaceutical Co., Ltd.
Appearance
White round tablet
Packaging
100 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 202100592 · Approved 2021.01.20 · Insurance code 642204520

Summary

Main use
Treatment of hyperthyroidism and preoperative treatment before thyroid surgery or radioiodine therapy
Who uses it
Adults · Children
Adult dosage
Adults: The initial daily dose of methimazole is administered orally in 3 divided doses at 8-hour intervals: 15mg for mild cases, 30-40mg for moderate cases, and 60mg for severe cases. As hyperthyroidism resolves, administer a maintenance dose of 5-15mg per day in 1-2 divided doses.
Children's dosage
Children: The initial daily dose of this medicine is 0.4mg/kg of body weight, administered in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, administer one-half of the initial dose as the maintenance dose.

Ingredients

Manufacturer
Bukwang Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of hyperthyroidism and preoperative treatment before thyroid surgery or radioiodine therapy

  • Hyperthyroidism
View approved original text

This medication is used for hyperthyroidism, particularly in patients who are planning thyroidectomy or radioactive iodine therapy. Hyperthyroidism is a condition characterized by excessive activation of the thyroid gland leading to an accelerated metabolism, and this medication helps alleviate symptoms by regulating thyroid function. Therefore, this medication is effective for both the treatment of hyperthyroidism and for preoperative preparation.

Dosage and Administration

Adult dosage

Adults: The initial daily dose of methimazole is administered orally in 3 divided doses at 8-hour intervals: 15mg for mild cases, 30-40mg for moderate cases, and 60mg for severe cases. As hyperthyroidism resolves, administer a maintenance dose of 5-15mg per day in 1-2 divided doses.

Children's dosage

Children: The initial daily dose of this medicine is 0.4mg/kg of body weight, administered in 3 divided doses at 8-hour intervals. As hyperthyroidism resolves, administer one-half of the initial dose as the maintenance dose.

Precautions

This medication should not be used in patients with certain blood disorders. For example, patients with agranulocytosis, leukopenia, or thrombocytopenia should not take this medication. Additionally, individuals with a history of allergic reactions to this medication or nursing women should not use it. This product contains lactose, and it should not be administered to patients with genetic lactose intolerance or related diseases. Patients with liver dysfunction or those who are pregnant or may become pregnant should use this medication with caution. Patients with blood disorders also require special attention. During the course of treatment with this medication, regular blood tests and liver function tests should be performed, and immediate consultation with a physician is necessary if side effects such as agranulocytosis, hepatitis, or skin abnormalities occur. Rarely, side effects such as skin rash, itching, nausea, vomiting, headache, and dizziness may occur, and in severe cases, discontinuation of the medication should be considered. This medication can increase the risk of hypothyroidism or bleeding, so coagulation status and thyroid function should be carefully checked before surgery. During pregnancy, it may affect the fetus, and women who may become pregnant should use effective contraception during treatment, while the minimum effective dose should be used cautiously in pregnancy. When taken with anticoagulants, there may be an increased risk of bleeding, so caution is advised when using both medications together. In case of overdose, symptoms such as vomiting, headache, skin rash, and blood abnormalities may appear, and appropriate medical treatment should be sought immediately. Long-term use of this medication at high doses may lead to thyroid abnormalities or other severe side effects, so it should be taken according to the physician's instructions.

Side effects

Agranulocytosis, leukopenia, hypoprothrombinemia, factor VII deficiency, thrombocytopenia, thrombocytopenic purpura, aplastic anemia, liver dysfunction, cholestatic hepatitis, jaundice, hair loss, skin pigmentation, itching, erythema, nausea, vomiting, diarrhea, loss of appetite, abdominal discomfort, malaise, acute pancreatitis, headache, dizziness, peripheral neuropathy, fatigue, drowsiness, rash, urticaria, fever, goiter, hypothyroidism, hepatitis, exfoliative dermatitis, neuritis, stimulation or inhibition of the central nervous system, periarteritis, lupus syndrome, hypoglycemic coma, lymphadenopathy, arthralgia, myalgia, salivary gland enlargement, edema, drug fever, sensory disturbances, loss of taste, nephritis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to light and should be stored in a tightly sealed container that blocks light. It is safest to store the medication at room temperature between 1°C and 30°C and avoid extremely hot or cold places.

Appearance and packaging

Appearance

White round tablet

Package unit

100 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.