Janglen Tablet 100 Milligrams (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered at a dose of 100 mg once daily for monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Patients with renal impairment may require dosage adjustments based on renal function. For mild renal impairment (glomerular filtration rate[eGFR] ≥ 60 and < 90 mL/min/1.73 m2) and moderate renal impairment (glomerular filtration rate[eGFR] ≥ 45 and < 60 mL/min/1.73 m2)

This medication can rarely cause severe allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking it, stop taking it immediately and seek medical advice. This medication can cause acute pancreatitis, a serious inflammation of the pancreas, so if symptoms such as abdominal pain, vomiting, or loss of appetite occur while taking it, consult a doctor immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication, nor should patients allergic to its components. Patients with impaired renal function need dose adjustment, so consult a doctor if there are any kidney diseases. While taking this medication, symptoms similar to a cold, headache, indigestion, diarrhea, etc., may occur, and hypoglycemic symptoms may also arise, so caution is necessary. Particularly, when taking insulin or sulfonylureas together, the risk of hypoglycemia increases, thus blood sugar levels should be checked frequently and doses of those medications adjusted if necessary. If symptoms of severe joint pain or skin blisters occur, stop taking this medication immediately and consult a healthcare professional. Pregnant or breastfeeding women are recommended not to take this medication, and safety and efficacy have not been established for individuals under 18 years of age. Elderly patients should have their renal function checked before and after taking this medication, and doses adjusted if necessary due to risks of renal impairment. In case of overdose, visit a medical institution immediately to receive appropriate treatment, and this medication can be partially removed through hemodialysis. There are minimal interactions with other medications, but when taking certain medications, consult with a doctor or pharmacist to use them safely.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, exfoliative skin disorders including Stevens-Johnson syndrome, acute pancreatitis, acute renal failure, severe and debilitating joint pain, blistering dermatitis, severe allergic reactions, angioedema, rash, vasculitis, elevated liver enzymes, liver abnormalities (jaundice), thrombocytopenia, rhabdomyolysis, severe hypoglycemia, cardiac arrest, pneumonia, diabetes complications, metabolic acidosis, falls, and heart complications.

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a sealed container to prevent air or moisture from entering. The recommended storage temperature is between 1 to 30 degrees Celsius at room temperature. Proper storage will help maintain the effectiveness of the medication for a long time.

Appearance

Light orange, round, biconvex film-coated tablet

Package unit

28 tablets - 14 tablets/PTP[x 2], 30 tablets - 10 tablets/PTP[x 3]