Jaglenteong 25 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The dosage for this medication is 100 mg once daily, whether used alone or in combination therapy, with a maximum daily dose of 100 mg. In patients with renal impairment, dose adjustment is necessary according to the glomerular filtration rate. - No dose adjustment is needed for mild and moderate renal impairment (eGFR 45-90 mL/min/1.73 m2). - For glomerular filtration rates of 30-45 mL/min/1.73 m2, administer 50 mg once daily. -

This medication may cause allergic reactions, so if symptoms such as skin rashes, difficulty breathing, or swelling of the face or neck occur after taking the medicine, stop taking it and consult a doctor immediately. This medication may cause acute pancreatitis, a serious inflammation of the pancreas, so if abdominal pain, vomiting, or loss of appetite occurs during treatment, go to the hospital immediately. Do not use this medication in patients with type 1 diabetes or diabetic ketoacidosis, and it should not be used if there is an allergy to this drug or its components. Patients with impaired kidney function need to adjust the dosage of this medication, especially those with severe renal impairment should take it with caution. Possible side effects when this drug is used alone or in combination with other diabetes medications include upper respiratory infections, nasopharyngitis, headaches, diarrhea, nausea, and may include hypoglycemic symptoms, so blood sugar control should be monitored closely. When administered with other hypoglycemic agents, especially insulin or sulfonylureas, the risk of hypoglycemia may increase, so dosage adjustments should be made according to a doctor's instructions. This drug is not recommended for use in women who are pregnant or breastfeeding, and its safety and efficacy have not been established in children or adolescents under 18 years of age. Elderly individuals may have decreased kidney function, therefore dose adjustments and kidney function tests are necessary. In cases of overdose, drug removal from the gastrointestinal tract and monitoring of the condition through ECG may be conducted, and if necessary, some drugs may be removed via hemodialysis. This medication does not have significant interactions with other drugs; however, blood concentration changes should be monitored when taken with digoxin or cyclosporine. If severe joint pain or skin blisters occur while taking this medication, inform your doctor immediately and stop taking the drug.

Serious side effects

Urticaria, angioedema, anaphylaxis, Stevens-Johnson syndrome and exfoliative skin diseases, acute pancreatitis, severe hypoglycemia, acute renal failure, severe and disabling arthralgia, bullous pemphigoid, pneumonia, diabetic complications, metabolic acidosis, cardiac arrest.

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• constipation
• vomiting
• myalgia
• limb pain
• back pain

Store this medication in a tightly closed container that does not allow air to enter, and it is recommended to store at room temperature between 1°C and 30°C. By doing so, the effectiveness of the medication can be well maintained.

Appearance

Pink, round, and bilaterally convex film-coated tablet

Package unit

28 tablets - 14 tablets/PPT[x 2], 30 tablets - 10 tablets/PPT[x 3]