Apeget Tablets 10/40 Milligrams

Adult dosage

This medication is administered once daily, regardless of meals. The dosage range is from 10/10mg to 10/40mg daily. A starting dose of 10/10mg or 10/20mg daily is recommended. For patients requiring more significant LDL cholesterol reduction, the dosage can be adjusted. After starting treatment or upon adjusting the dosage, blood lipid levels should be checked after intervals of more than 2 weeks before adjusting the dose.

This medication may cause a rare side effect called rhabdomyolysis, which can lead to serious muscle problems. This may result in a rapid deterioration of kidney function; therefore, patients should consult a physician immediately if acute muscle pain or weakness occurs. This medication should not be used in patients with allergies to the active ingredient or constituents, patients with severely impaired liver function, patients with muscle disorders, pregnant women or women who may become pregnant, nursing mothers, patients currently taking certain antiviral agents, and patients with lactose intolerance. Caution should be exercised when administering this medication to patients with a history of alcohol abuse or liver disease, patients with moderate to severe liver impairment, patients with weak kidney function or hypothyroidism, and elderly patients who are at higher risk for myopathy. Patients taking this medication should have regular liver function tests and muscle-related examinations, and should inform healthcare providers immediately if symptoms such as abnormal liver function, muscle pain, muscle weakness, or muscle cramps occur. This medication may interact with other drugs; patients should inform their physician of all medications they are currently taking, especially when used in combination with certain antibiotics, antivirals, immunosuppressants, and fibrates. Women of childbearing potential should use appropriate contraceptive methods while taking this medication and must not take it during pregnancy. This medication is not recommended for children as its safety and efficacy have not been established in this age group. Elderly patients are at higher risk for myopathy; caution should be exercised during administration, although dose adjustment is usually not necessary. Patients with impaired liver or kidney function must consult with their physician before taking this medication, and it should not be administered in cases of severe liver impairment. In case of overdose, there is no specific antidote, so appropriate treatment and supportive care should be administered based on symptoms, and regular liver function and muscle-related tests should be conducted. This medication should be kept out of the reach of children and not transferred to other containers for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attack, respiratory difficulties accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urinary issues

Mild side effects

• Decreased sensation
• abnormal sensation
• hypertension
• increased ALT
• increased GGT
• nasopharyngitis
• cough
• itching
• dizziness
• diabetes

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius at room temperature.

Appearance

White oval film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP x 3)], 30 tablets/bottle, 100 tablets/bottle