Medication info
Atoriv 10/20 mg Tablets

Atoriv 10/20 mg Tablets

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium›21.7mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
화일약품(주)
Appearance
White oval film-coated tablets
Packaging
30 tablets/box [10 tablets/Alu-Alu x 3]
Approval status
Active

MFDS item code 202100229 · Approved 2021.01.08 · Insurance code 684502060

Summary

Main use
Improvement of cholesterol and lipids in patients with hypercholesterolemia (primary, mixed) and dyslipidemia
Who uses it
Adults
Adult dosage
This medication should be taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/40mg daily. The recommended starting dose is 10/10mg or 10/20mg once daily. Patients requiring greater reduction of LDL cholesterol may have their dosage adjusted. After starting treatment or adjusting dosages, blood lipid levels should be checked with intervals of at least two weeks.

Ingredients

Manufacturer
화일약품(주)

Efficacy & effects

Improvement of cholesterol and lipids in patients with hypercholesterolemia (primary, mixed) and dyslipidemia

  • Primary hypercholesterolemia
  • dyslipidemia
  • increased total cholesterol
  • LDL cholesterol
  • Apo B protein
  • triglycerides
  • non-HDL cholesterol
View approved original text

This medication helps to lower total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol levels while increasing HDL cholesterol levels in patients with primary hypercholesterolemia, which may be due to genetic or other causes, and mixed dyslipidemia. It can effectively regulate blood lipid levels when used in conjunction with dietary interventions and contributes to reducing the risk of cardiovascular diseases. However, this medication has limited research for certain types of dyslipidemia and should be used cautiously considering other composite risk factors. Additionally, it is important to check for the presence of other conditions that may cause dyslipidemia, such as thyroid dysfunction, diabetes, or liver disease, before taking this medication, and it is crucial to undergo proper testing and dietary management. Proper management can improve blood lipid levels and effectively reduce the risk of atherosclerotic diseases.

Dosage and Administration

Adult dosage

This medication should be taken once daily, regardless of meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/40mg daily. The recommended starting dose is 10/10mg or 10/20mg once daily. Patients requiring greater reduction of LDL cholesterol may have their dosage adjusted. After starting treatment or adjusting dosages, blood lipid levels should be checked with intervals of at least two weeks.

Precautions

This medication carries a risk of muscle-related issues, so if any severe muscle pain or weakness occurs, you must consult a healthcare professional immediately. Particularly in cases of severe infection, hypotension, major surgery, trauma, or severe metabolic disturbances, the use of this medication may need to be temporarily stopped or discontinued. Patients who are allergic to any components of this medication or have active liver disease, muscle disorders, or who are pregnant or nursing should not use it. Additionally, patients with issues related to lactose components in this medication should avoid taking it. Patients with a history of alcohol abuse or liver disease, those with impaired kidney function, or hypothyroidism should use this medication cautiously. Elderly patients over 70 years or those with a history of muscle toxicity should also use it carefully. While taking this medication, regular liver function tests are necessary, and symptoms of liver dysfunction (e.g., nausea, vomiting, fatigue) should be reported immediately. This medication may interact with other drugs, so it is crucial to inform your physician or pharmacist about any other medications you are taking. Caution is especially needed when taken with certain antibiotics, antivirals, and immunosuppressants, as the risk of muscle damage may increase. Women of childbearing age should use adequate contraception during treatment and must stop taking it immediately if pregnancy is confirmed. This medication is not recommended for children, as safety and efficacy have not been established. In the case of overdose, there is no specific antidote; treatment should be symptomatic, and liver and muscle enzyme tests should be performed. This medication should be kept out of the reach of children, and it should not be transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough + fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination problems

Mild side effects

  • Headache
  • dizziness
  • paresthesia
  • itching
  • chest pain
  • peripheral edema
  • fatigue
  • fever
  • rhinitis
  • cough
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  • hypertension
  • diabetes
  • insomnia
  • nightmares
  • myalgia
  • arthralgia
  • muscle cramps
  • sore throat
  • urticaria
  • skin rash
  • hair loss
  • sweating
  • eczema
  • seborrhea
  • skin ulcers
  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pharyngolaryngeal pain
  • epistaxis
  • tinnitus
  • blurred vision
  • anemia
  • thrombocytopenia
  • hypoglycemia

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is safe to store at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/box [10 tablets/Alu-Alu x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.