L-O-Gongjeong 10/10 mg

Adult dosage

This medication is administered once daily, irrespective of meals. The dosage range is 10/10 mg to 10/40 mg daily, with a recommended initial dose of 10/10 mg or 10/20 mg daily. For patients requiring a greater reduction in LDL-cholesterol, dosage can be adjusted. Blood lipid levels should be checked at intervals of more than 2 weeks after initiating treatment or adjusting the dosage.

This medication has been reported to cause a rare side effect called rhabdomyolysis, which can result in serious muscle damage. Patients should immediately inform their physician if they experience severe muscle pain or weakness. In cases of renal impairment, severe infections, post-major surgery, or hypotension, it may be necessary to temporarily discontinue or stop this medication. Patients with known allergies to specific components, those with severe liver dysfunction, those with muscle diseases, pregnant or potentially pregnant women, and breastfeeding women should not take this medication. Additionally, patients currently on glecaprevir and pibrentasvir or those with lactose intolerance should avoid it. Patients with a history of liver disease, those with alcohol abuse, reduced renal function, hypothyroidism, the elderly, and those with a family history of muscle disease should take this medication with caution, and consult a physician immediately if they experience muscle pain or weakness. Regular liver function tests and muscle-related tests should be conducted while taking this medication, and if liver function levels are abnormally high or if muscle-related levels increase significantly, the medication should be discontinued. This medication may interact with various other drugs, so patients should inform their physician or pharmacist if they are taking other medications. The risk of muscle damage may increase when taken with drugs that interfere with hepatic drug metabolism. Pregnant or breastfeeding women should not take this medication, and women of childbearing age should use effective contraception while on this medication. This medication is not recommended for children as its safety and efficacy have not been established. In cases of overdose, there is no specific antidote, so treatment should be based on symptoms, and liver function and muscle-related tests should be monitored. Caution is advised if dizziness occurs while driving or operating machinery during the use of this medication. Store out of reach of children and do not transfer to other containers for safety.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory difficulties accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme fatigue, sudden and severe headaches, thunderclap headache, seizures, confusion, vision changes, paralysis, urination problems

Mild side effects

• Fatigue
• chest pain
• peripheral edema
• lethargy
• nasopharyngitis
• cough
• itching
• dizziness
• headache
• diarrhea

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius to ensure the efficacy and safety of the medication over time.

Appearance

White oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP*3], 30 tablets/bottle