Wyjett Tablets 10/20 mg

Adult dosage

This medication is administered once daily, regardless of meals. The recommended initial dosage is 10/10 mg or 10/20 mg per day. The dosage range is 10/10 mg to 10/40 mg per day. For patients who require a greater reduction in LDL-cholesterol, dosages may be adjusted. After starting the medication or adjusting the dosage, blood lipid levels should be checked after an interval of more than 2 weeks before adjusting the dosage.

This medication has been reported to cause a rare side effect called rhabdomyolysis, which can lead to serious muscle issues. It is particularly necessary to discontinue this medication temporarily or permanently in patients showing severe myopathy symptoms or at risk for acute renal failure. Patients allergic to this medication or its components, those with very severe liver dysfunction or active liver disease, patients with muscle diseases, pregnant women or those who may become pregnant, breastfeeding women, and patients taking certain antiviral medications should not take this medication. Alcoholics or patients with a history of liver disease, those with reduced kidney function, hypothyroidism, or a history of genetic muscle disorders should use this medication with caution, as should elderly patients. Patients taking fibrate-class medications and those with severe muscle weakness should also be cautious. Symptoms such as muscle pain, muscle cramps, muscle weakness, fatigue, fever, etc. should be reported to a doctor immediately during the course of this medication, and blood tests should be performed to check for muscle damage. Liver function abnormalities may occur, so it's important to conduct liver function tests before starting treatment and during treatment. This medication should not be administered to pregnant or breastfeeding women, and women of childbearing age should use appropriate contraception. Furthermore, due to numerous drug interactions, it is essential to inform the physician or pharmacist about current medications being taken, especially when taken with certain antibiotics, antivirals, immunosuppressants, or fibrate-class medications. This medication's safety in children has not been established, and elderly patients have a higher risk of myopathy, thus caution is necessary during use. There is no specific antidote for overdose, hence treatment should follow symptomatically with liver function and muscle enzyme tests as needed. Finally, this medication should be stored out of reach of children and it is advisable not to transfer it to other containers.

Serious side effects

• Urticaria
• severe swelling (edema)
• Stevens-Johnson syndrome (SKS)
• toxic epidermal necrolysis (TEN)
• erythema multiforme
• jaundice
• rhabdomyolysis
• myopathy
• liver failure
• severe allergic reactions

Mild side effects

• Decreased sensation
• abnormal sensation
• hypertension
• increased ALT
• increased GGT
• nasopharyngitis
• cough
• itching
• dizziness
• diabetes

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. To maintain the medication's effectiveness, it is important to store it at room temperature, between 1 to 30 degrees Celsius.

Appearance

White oval film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP*3], 30 tablets/bottle