Medication info
Utojet Tablet 10/10mg

Utojet Tablet 10/10mg

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium›10.85mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
(주)유유제약
Appearance
White oval film-coated tablets
Packaging
30 tablets/box [10 tablets/PTP (×3)], 30 tablets/bottle
Approval status
Active

MFDS item code 202100193 · Approved 2021.01.08 · Insurance code 644503250

Summary

Main use
Improvement of lipids by reduction of cholesterol in hypercholesterolemia and dyslipidemia and increase of HDL
Who uses it
Adults
Adult dosage
This medication is taken once daily without regard to food. For primary hypercholesterolemia, a dosage range of 10/10mg to 10/40mg daily is used, with the recommended initial dose being 10/10mg or 10/20mg per day. Patients requiring a more significant reduction in LDL cholesterol may adjust the dosage. After initiating therapy or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks.

Ingredients

Manufacturer
(주)유유제약

Efficacy & effects

Improvement of lipids by reduction of cholesterol in hypercholesterolemia and dyslipidemia and increase of HDL

  • Primary hypercholesterolemia
  • dyslipidemia
  • elevated total cholesterol
  • LDL cholesterol
  • Apo B protein
  • triglycerides
  • non-HDL cholesterol
View approved original text

This medication helps regulate blood cholesterol and related lipid levels in patients with primary hypercholesterolemia, particularly heterozygous familial and non-familial forms, as well as mixed dyslipidemia. It lowers total cholesterol, LDL cholesterol, Apo B protein, triglycerides, and non-HDL cholesterol while raising HDL cholesterol levels known as 'good cholesterol', contributing to cardiovascular health improvement. Additionally, this medication is used as an adjunct when non-pharmacological treatments with appropriate dietary management are not sufficiently effective. It's important to identify and treat other secondary causes like diabetes and hypothyroidism before treatment, and regular lipid tests should be conducted during therapy to monitor the condition. This medication is especially effective when there is a high risk of atherosclerotic vascular diseases and is used for the prevention and management of cardiovascular diseases. Therefore, this medication aids in the health management of dyslipidemia patients and improves the risk of cardiovascular diseases.

Dosage and Administration

Adult dosage

This medication is taken once daily without regard to food. For primary hypercholesterolemia, a dosage range of 10/10mg to 10/40mg daily is used, with the recommended initial dose being 10/10mg or 10/20mg per day. Patients requiring a more significant reduction in LDL cholesterol may adjust the dosage. After initiating therapy or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks.

Precautions

Serious side effects such as rhabdomyolysis, which can cause severe muscle damage, have been reported for this medication. Therefore, if serious muscle pain or weakness occurs, it should be immediately reported to a doctor. This medication should be temporarily discontinued or stopped in patients with poor kidney function, serious infections, hypotension, or after major surgery. Patients with allergies to any of the components, active liver diseases, pregnant women, women who may become pregnant, and nursing mothers should not use this medication. Patients with muscle disease or those taking Glecaprevir and Pibrentasvir should also refrain from using this medication. Caution is also needed for alcoholics, patients with impaired liver function, patients at risk of certain myopathies, elderly patients, and those taking fibrate class medications. During the course of treatment with this medication, liver function tests and muscle-related tests should be conducted regularly, and if there are liver function abnormalities or worsening muscle pain, it should be discussed with a doctor immediately. This medication has many interactions with other drugs, so dosage adjustment or cessation may be necessary when taken with specific antibiotics, antivirals, cyclosporine, or fibrate class drugs. This medication should not be used during pregnancy or while breastfeeding as it may pose risks to the fetus and baby. Safety in children has not been established; therefore, it is not recommended for children. Elderly individuals should also be cautious due to the increased risk of myopathy. There is no specific antidote for overdose, and treatment should be based on symptoms while monitoring liver function and muscle enzyme levels. It is advised to keep this medication out of reach of children and not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in mouth/eye mucous membranes, shortness of breath or difficulty breathing, asthma attacks, cough with fever along with respiratory abnormalities, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination issues

Mild side effects

  • Fatigue
  • chest pain
  • peripheral edema
  • lethargy
  • fever
  • nasopharyngitis
  • cough
  • itching
  • dizziness
  • headache
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  • hypertension
  • diabetes
  • constipation
  • abdominal bloating
  • dyspepsia
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • burping
  • pharyngeal/laryngeal pain
  • nosebleed
  • insomnia
  • nightmares
  • altered perception
  • sensory loss
  • altered taste
  • amnesia
  • myalgia
  • arthralgia
  • limb pain
  • muscle cramps
  • joint swelling
  • back pain
  • neck pain
  • muscle fatigue
  • thrombocytopenia
  • hepatitis
  • bile

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air and moisture from entering, ideally at room temperature between 1 and 30 degrees. Proper storage will help maintain the medication's effectiveness for a longer period.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP (×3)], 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.