Atovjet Tablets 10/40 Milligrams

Adult dosage

This medication is administered once daily without regard to meals. For primary hypercholesterolemia, the dosage range is 10/10mg to 10/80mg; the recommended starting dose is 10/10mg or 10/20mg daily. For patients requiring more significant reductions of LDL-cholesterol, a starting dose of 10/40mg daily is recommended. Dose adjustments should be made after checking lipid levels at intervals of at least 2 weeks.

This medication carries a risk of serious muscle issues, so if sudden muscle pain or weakness occurs, medical personnel should be informed immediately. In cases of severe infections, hypotension, major surgery, trauma, or metabolic disorders, the use of this medication may need to be temporarily discontinued or stopped. Patients with allergies to any of the components of this medication, active liver disease, muscle disorders, women who are pregnant or breastfeeding, and patients on certain antiviral treatments should not take this medication. Caution is also required for patients with a history of alcohol dependence or liver disease, poor kidney function, or hypothyroidism. Since this medication may affect liver function, regular liver function tests should be performed before and during treatment. During the course of this medication, symptoms such as muscle pain, fatigue, and fever may appear; if these symptoms are severe or persistent, consultation with medical personnel is advised. This medication can interact with other drugs, so patients should inform their healthcare provider of any medication they are currently taking, especially if it includes certain antibiotics, antivirals, or immunosuppressants. Women of childbearing age should use appropriate contraceptive measures to prevent pregnancy while on this medication and should discontinue use immediately if pregnancy is confirmed. Caution is needed while driving or operating machinery due to the possibility of symptoms such as dizziness. In case of overdose, as there is no specific antidote, appropriate treatment should be administered based on symptoms while monitoring liver and muscle conditions. This medication is not recommended for children as its safety and effectiveness in this population have not been established. Elderly patients have a higher risk of muscle issues; however, dose adjustment is generally not necessary. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory complications accompanied by cough and fever, skin or eye yellowing (jaundice), profound general weakness, sudden severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Muscle pain
• abdominal pain
• elevated liver enzymes
• dizziness
• cough
• nausea
• diarrhea
• joint pain
• muscle weakness
• musculoskeletal pain

This medication should be stored in a tightly sealed container to prevent air and moisture ingress and should be kept at room temperature between 1°C and 30°C. Storing it this way helps maintain its effectiveness and prevent degradation.

Appearance

White oblong film-coated tablets

Package unit

PTP packaging - 30 tablets/box [10 tablets/PTP packaging (Alu-Alu) x 3], bottle packaging - 30 tablets/bottle, bottle packaging - 100 tablets/bottle