Medication info
AtorTive Tablet 10/10 mg

AtorTive Tablet 10/10 mg

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium›10.85mg / 1 tabletEzetimibe›10mg / 1 tablet
Manufacturer / importer
한국휴텍스제약(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202100174 · Approved 2021.01.08 · Insurance code 649105140

Summary

Main use
Improvement of cholesterol and lipid levels in hypercholesterolemia (primary, mixed) and dyslipidemia
Who uses it
Adults
Adult dosage
The medication is administered once daily regardless of meals. The dosage range is 10/10mg to 10/40mg daily. An initial dosage of 10/10mg or 10/20mg daily is recommended. For patients requiring more LDL cholesterol reduction, the dosage can be adjusted. After starting treatment or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks to adjust the dosage accordingly.

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Improvement of cholesterol and lipid levels in hypercholesterolemia (primary, mixed) and dyslipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed dyslipidemia
  • elevated total cholesterol
  • elevated LDL cholesterol
  • elevated apo B protein
  • elevated triglycerides
  • elevated non-HDL cholesterol
View approved original text

This medication helps lower various lipid levels, including high total cholesterol and LDL cholesterol, in patients with primary hypercholesterolemia, while increasing HDL cholesterol, the good cholesterol. It is used as an adjunct when dietary changes alone do not produce sufficient effects and may reduce the risk of cardiovascular diseases. It is important to identify and treat secondary causes of dyslipidemia, such as diabetes and hypothyroidism, before starting treatment. Lipid levels should be regularly monitored, especially in patients with acute coronary events, who should be tested early during hospitalization. This medication works alongside appropriate dietary adjustments to improve hypercholesterolemia.

Dosage and Administration

Adult dosage

The medication is administered once daily regardless of meals. The dosage range is 10/10mg to 10/40mg daily. An initial dosage of 10/10mg or 10/20mg daily is recommended. For patients requiring more LDL cholesterol reduction, the dosage can be adjusted. After starting treatment or adjusting the dosage, blood lipid levels should be checked at intervals of more than 2 weeks to adjust the dosage accordingly.

Precautions

This medication can affect the muscles, so if symptoms such as muscle pain, muscle cramps, or muscle weakness occur, you should consult your doctor immediately. Severe muscle disorders or rhabdomyolysis, which are rare side effects, may occur, so caution is needed if there is muscle pain or weakness accompanied by fever. Liver function tests should be conducted before and during treatment with this medication, and if there is an abnormality in liver function, administration should be stopped or the dosage adjusted. Additionally, this medication should be used cautiously in patients with liver disease or those who consume excessive alcohol. Women who are pregnant or may become pregnant, as well as nursing mothers, should not take this medication, and women of childbearing age should use appropriate contraception during treatment. It is not recommended for children as safety and efficacy have not been established. Elderly patients are at higher risk of muscle disorders, so caution is needed when taking this medication, although specific dosage adjustments are generally not required. This medication may increase the risk of side effects when taken with certain other drugs, so you should inform your doctor or pharmacist if you are taking other medications. There is no specific antidote for overdose, so supportive treatment should be administered alongside monitoring of liver function and muscle enzyme levels. When storing, it should be kept out of reach of children and not transferred to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucous membranes, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), profound fatigue, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination changes

Mild side effects

  • Headache
  • dizziness
  • paresthesia
  • itching
  • hypertension
  • nasopharyngitis
  • cough
  • fatigue
  • abdominal pain
  • diarrhea
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  • nausea
  • constipation
  • pharyngitis
  • sinusitis
  • weight gain
  • loss of appetite
  • dyspepsia
  • vomiting
  • belching
  • pancreatitis
  • throat and larynx pain
  • nosebleed
  • insomnia
  • nightmares
  • muscle pain
  • joint pain
  • limb pain
  • muscle cramps
  • joint swelling
  • back pain
  • neck pain
  • muscle fatigue
  • thrombocytopenia
  • hepatitis
  • blurred vision
  • tinnitus
  • hearing loss
  • skin rash
  • hair loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent contact with air or moisture. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius. This helps to preserve the medication's efficacy and safety for a longer period.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.