Olmesartan Medoxomil and Rosuvastatin Tablets 20/20 mg

Adult dose

Olmesartan Medoxomil The recommended starting dose is 10 mg once daily, administered regardless of food. If blood pressure is not adequately controlled, it can be increased to 20 mg once daily, and can be increased up to a maximum of 40 mg. It may be co-administered with diuretics such as hydrochlorothiazide. Rosuvastatin The starting dose is 5 mg once daily, and the maintenance dose can be adjusted as needed. The maintenance dose is once daily.

Child dose

The safety and efficacy in pediatric patients under 18 years of age have not been established.

This drug can cause serious harm to the fetus and newborn when taken during the second and third trimester of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. This medication should not be administered to individuals with known allergies to its ingredients, to pregnant or potentially pregnant women, or to breastfeeding women. Use is contraindicated in patients with severely impaired renal function, those undergoing renal dialysis, patients with severe liver impairment, and those with biliary obstruction. Patients with a history of muscle disorders or those prone to muscle issues should avoid high-dose administration of this medication, especially the 40 mg dose which is contraindicated. This drug contains lactose and should not be used by patients with lactose intolerance or related genetic disorders. In patients with low blood pressure or decreased salt or blood volume, hypotension may occur if administered, and appropriate treatment is required immediately if hypotension symptoms arise. Patients who are dependent on renal function may experience worsening renal function, thus routine blood tests should be done to monitor renal function periodically. As there is a risk of hyperkalemia, serum potassium levels should be monitored regularly, and caution is needed in patients with heart or lung problems. This medication may affect liver function, so patients with a history of liver disease or those consuming excessive alcohol should have regular liver function tests. In cases of muscle pain or weakness, the healthcare provider should be notified immediately, and if severe, medication should be stopped. This drug may interact with other medications; special caution is required particularly when co-administered with potassium-sparing diuretics, lithium, non-steroidal anti-inflammatory drugs, specific antivirals, and fibrates. Pregnant or breastfeeding women should not take this drug, and women who could become pregnant should use appropriate contraception. Extra caution is required when administering this drug to children under 18 years of age and to elderly patients over 65 years, as elderly patients may show increased drug concentration in the body. In case of overdose, symptoms such as hypotension and palpitations may occur, and appropriate treatment should be administered through liver function and muscle-related tests. This medication should be kept out of the reach of children and should not be transferred to another container.

Serious side effects

Hives, severe swelling (edema), angioedema, tightness in the chest, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), severe fatigue, sudden and extremely severe headache, thunderclap headache, seizures, confusion, visual disturbances,

Mild side effects

• Headache
• dizziness
• sensory disturbance
• drowsiness
• gastroesophageal reflux
• constipation
• dental caries
• dyspepsia
• gastric ulcers
• gastritis

This medication may be sensitive to air or moisture; therefore, it must be stored in a sealed container. The storage temperature should be maintained between 1°C and 30°C at room temperature to safely preserve the efficacy of the drug.

Appearance

White or light yellow round film-coated tablets

Package unit

30 tablets/box [30 tablets (10 tablets/PTP x 3)]