Sida Tablet 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The usual dosage for this medication is 100 mg once daily, either as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Dosage adjustment is required based on kidney function, with the following recommendations: 1. Mild renal impairment (eGFR 60-90 mL/min/1.73 m2): No dosage adjustment needed. 2. Moderate renal impairment (eGFR 45-60 mL/min/1.73 m2):

This medication may rarely cause severe allergic reactions; therefore, if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after administration, discontinue use immediately and consult a healthcare professional. This medication can trigger acute pancreatitis, which is a serious inflammation of the pancreas. If symptoms such as abdominal pain, nausea, or vomiting occur, inform a physician immediately. This medication should not be used in patients with type 1 diabetes or those with diabetic ketoacidosis, nor in individuals who are hypersensitive to this drug or its components. Patients with impaired kidney function may slow the excretion of this drug, so dosage adjustment or careful administration is necessary, along with regular monitoring of kidney function. Hypoglycemia may occur when using this drug alone or in combination with other diabetes medications, so be vigilant for symptoms of hypoglycemia and adjust the dosage of other medications as needed. Headache, upper respiratory infections, nasopharyngitis, diarrhea, nausea, and other symptoms may occur during treatment; if symptoms are severe or persistent, consult a physician. This medication is not recommended for use during pregnancy, and nursing mothers should also avoid taking it. It is advisable not to use in children or adolescents under 18 years of age as safety and efficacy have not been established. Elderly patients may have an increased risk of impaired kidney function, and careful evaluation of kidney function should be performed regularly before and after starting treatment, adjusting the dosage as necessary. In cases of overdose, standard emergency procedures such as gastrointestinal decontamination should be carried out, and if necessary, some of the drug may be removed by hemodialysis. This drug has relatively few interactions when used with specific medications; however, caution is advised when used concurrently with other hypoglycemic agents or specific medications, as the risk of hypoglycemia may increase. If severe joint pain or blistering skin disease occurs during treatment, consult a physician immediately to decide whether to discontinue the medication.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor (severe hypersensitivity reactions and anaphylaxis), severe rash with high fever, blisters, skin peeling, mucosal pain in the mouth/eyes (severe skin reactions such as Stevens-Johnson syndrome), shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanying respiratory abnormalities (respiratory problems), yellowing of the skin or eyes (jaundice), malaise

Mild side effects

• Upper respiratory infections
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• extremity pain

Store this medication in a tightly closed container that prevents air and moisture from entering, and maintain at room temperature between 1 to 30 degrees Celsius. This storage helps to preserve the effectiveness of the medication over time.

Appearance

Pale orange, round, bi-convex film-coated tablet

Package unit

28 tablets/box [14 tablets/PTP x 2]