Sidabec 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily as sitagliptin at a dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments are needed based on renal function. - Mildly impaired renal function (eGFR 60–90 mL/min/1.73 m2): No dosage adjustment necessary. - Moderately impaired renal function (eGFR 45–60 mL/min/1.73 m2): Dosage adjustment may be required.

This medication is used for the treatment of diabetes and there are several precautions to consider while taking it. First, severe allergic reactions may occur during the use of this medication, so if symptoms such as skin rash, swelling, or difficulty breathing occur, discontinue use immediately and consult a doctor. Second, this medication can cause serious side effects such as pancreatitis, which is inflammation of the pancreas; therefore, if symptoms like abdominal pain, vomiting, or nausea appear, inform healthcare providers immediately. Third, this medication should not be used by patients with type 1 diabetes or diabetic ketoacidosis. Fourth, patients with decreased kidney function may have difficulties with drug excretion, requiring dose adjustments and regular kidney function tests. Fifth, when taken with other hypoglycemic agents or insulin, the risk of hypoglycemia may increase, so be attentive to symptoms of hypoglycemia and adjust doses of other medications as needed. Sixth, some patients may experience side effects such as joint pain or skin diseases, so it is important to consult with a physician if symptoms appear. Seventh, it is not recommended for women who are pregnant or nursing, and for children under 18 years, as the safety of this medication has not been established. Finally, if overdose occurs, visit a medical facility immediately for appropriate treatment, as this medication can be partially removed through hemodialysis, which should be considered for patients with severely impaired kidney function.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, chest tightness, difficulty breathing, cold sweats, pallor, severe hypersensitivity reactions, Stevens-Johnson syndrome, exfoliative dermatosis, severe rash with fever, blisters, skin peeling, oral/ocular mucosa pain, acute pancreatitis, fatal/non-fatal hemorrhagic or necrotizing pancreatitis, elevated liver enzymes, jaundice (skin or eyes turning yellow), profound lethargy

Mild side effects

• Rhinitis
• upper respiratory infection
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air entry, and it is best to keep it at room temperature between 1 degree and 30 degrees. This helps maintain the effectiveness of the medicine.

Appearance

Light orange, round, bilayer, convex film-coated tablet

Package unit

28 tablets/box [14/PTP x 2]