Sitauni Tablet 50 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

The recommended dosage for this medication is 100 mg once daily, whether used alone or in combination, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary, but mild and moderate renal impairment patients (eGFR 45 or more) do not require adjustments. For moderate renal impairment patients (eGFR between 30 and 45), the dosage is 50 mg once daily.

This medication may cause severe allergic reactions after administration; if symptoms such as rash or difficulty breathing occur, discontinue use immediately and consult a physician. Pancreatitis may occur when using this medication, so notify healthcare providers immediately if symptoms such as abdominal pain or vomiting arise. Patients with type 1 diabetes or those allergic to this medication should not take it. Patients with impaired renal function may require dosage adjustments, and regular kidney function tests are important. While taking this medication, hypoglycemic symptoms may occur, so blood sugar should be checked regularly, especially when taken with other hypoglycemic agents such as insulin or sulfonylureas. Possible side effects during treatment include headache, upper respiratory infections, nasopharyngitis, diarrhea, nausea, and others. Pregnant or breastfeeding women are advised not to take this medication, and safety in children and adolescents under 18 has not been established. Elderly patients may have reduced kidney function, so dosage adjustments and monitoring of kidney function are necessary. In case of overdose, go to a hospital immediately for appropriate treatment; this medication can be partially removed by hemodialysis. This medication has relatively few interactions with other drugs, but caution is required when taken with digoxin, and consultation with a doctor or pharmacist is recommended. Report and seek treatment immediately if any adverse symptoms such as joint pain or skin blisters occur while taking this medication.

Serious side effects

Urticaria, severe hypersensitivity reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome, and other exfoliative skin diseases), severe rash, acute pancreatitis, liver abnormalities (elevated liver enzymes, possible jaundice), severe hypoglycemia, acute renal failure, severe joint pain with disability, bullous pemphigoid, rhabdomyolysis, cardiac arrest, pneumonia, diabetes complications, metabolic acidosis, severe edema

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• dyspepsia
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain

Store this medication in a tightly sealed container to prevent exposure to air and moisture, at room temperature between 1 and 30 degrees Celsius. This will help maintain the drug's effectiveness and prevent degradation.

Appearance

Light yellow pink round, biconvex film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP×3)]