Sitauni Tablet 25 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, with a maximum dose of 100 mg per day. It can be taken regardless of meals. Patients with renal impairment need dosage adjustment according to renal function. Mild and some moderate renal impairment patients do not require dosage adjustment, while moderate renal impairment patients are given 50 mg once daily. Severe renal impairment and end-stage renal disease patients receive 25 mg once daily.

This medication may cause serious allergic reactions, and if symptoms such as skin rash or difficulty breathing occur, the patient should stop taking it immediately and consult a doctor. During the use of this medication, pancreatitis, an inflammation of the pancreas, can occur. Therefore, if symptoms such as abdominal pain, vomiting, or loss of appetite arise, a hospital visit is necessary. It should not be administered to patients with type 1 diabetes or diabetic ketoacidosis, and those allergic to this medication or its components should also avoid it. Patients with impaired kidney function may need to adjust the dosage of this medication and undergo regular kidney function tests. There is a risk of hypoglycemia when taking this medication, especially if used with insulin or sulfonylureas. Therefore, careful monitoring of blood sugar levels should be conducted, and dosage adjustments may be necessary. Rarely, side effects such as arthralgia or skin vesicles have been reported, so a doctor should be consulted if such symptoms appear. Pregnant or breastfeeding women should avoid taking this medication, and its safety has not been established for children or adolescents under 18 years old. Elderly patients may experience a decline in kidney function, so evaluating kidney function before use and adjusting the dosage may be necessary. In case of overdose, symptomatic treatment such as removing the medication from the gastrointestinal tract should be performed, and hemodialysis may be considered as it can remove some of the drug. This medication has minimal interactions with other diabetes treatments or some medications, but caution is needed as digoxin levels may slightly rise when taken together. It is important to consult a doctor or pharmacist immediately if any abnormal symptoms or side effects occur during use.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, anaphylaxis, Stevens-Johnson syndrome, severe rash with high fever, blistering, skin peeling, pain in oral/ocular mucosa, acute pancreatitis, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory distress, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures

Mild side effects

• Rhinitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• constipation
• vomiting
• myalgia
• limb pain
• back pain

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and the storage temperature should maintain room temperature between 1 degree and 30 degrees. This will help to keep the drug's effectiveness safe for an extended period.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP×3)]