Sitagliptin 100 mg Tablets (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered as 100 mg once daily for either monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. Renal impairment dosage adjustment guidelines: - Mild renal impairment (eGFR 60-90): no dosage adjustment required - Moderate renal impairment (eGFR 45-60): no dosage adjustment required - Moderate renal impairment (eGFR 30-45): administer 50 mg once daily

This medication may cause allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a doctor. While taking this medication, there is a risk of developing acute pancreatitis, a serious inflammation of the pancreas, so it is crucial to inform healthcare professionals immediately if symptoms such as abdominal pain, vomiting, or loss of appetite appear. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication, nor should those who are allergic to this medication or its components. Patients with impaired renal function need to adjust the dosage of this medication, so regular kidney function tests should be conducted, and the advice of a doctor should be followed. Some patients reported symptoms such as cold symptoms, headaches, and digestive disorders when taking this medication alone or in combination with other diabetes medications. If these symptoms are severe, consult healthcare professionals. When taken with other hypoglycemic agents, especially insulin or sulfonylureas, there may be an increased risk of hypoglycemia, so glucose levels should be checked frequently, and immediate action should be taken if symptoms occur. If any abnormal symptoms such as severe joint pain or skin blisters occur while taking this medication, discontinue use immediately and seek consultation from a specialist. Pregnant or nursing women should avoid using this medication, and children under 18 years of age should not take it as safety and efficacy have not been established. Elderly patients are at a higher risk of impaired renal function, so dosage adjustments and regular kidney function tests are necessary. In case of overdose, general treatment such as removing the drug from the gastrointestinal tract should be performed, and if necessary, some drugs may be removed by hemodialysis. Therefore, it is essential to visit a medical facility immediately in emergency situations. This drug has relatively few interactions with other medications, but if the patient is taking certain drugs, they should inform their doctor or pharmacist.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, chest tightness, difficulty breathing, pallor, cold sweat (severe allergic reaction), severe rash with fever, blistering, skin shedding, pain of oral or ocular mucous membranes (severe skin reactions), acute pancreatitis, elevated liver enzyme levels, yellowing of the skin or eyes (jaundice), profound lethargy (liver issues), severe joint pain with disabilities, bullous pemphigoid

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain a room temperature between 1 and 30 degrees Celsius. Proper storage will help retain the medication's effectiveness over a long period.

Appearance

Pale orange, round, bi-convex, film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP × 3]