Medication info

Multimineral 5 Weeks

Prescription medicationInjections정맥
Ingredient · strength
Zinc Sulfate Hydrate›4.39mg / 1mLCupric Sulfate Hydrate›1.57mg / 1mLManganese Sulfate Hydrate›0.308mg / 1mLChromic Chloride Hydrate›20.5μg / 1mLSelenious Acid›32.7μg / 1mL
Manufacturer / importer
(주)오스코리아제약
Appearance
A colorless or slightly blue transparent liquid in a colorless transparent vial, injection solution.
Packaging
10 vials/box [10 mL/vial x 10]
Approval status
Active

MFDS item code 202008004 · Notified 2020.11.19

Summary

Main use
Improvement of nutritional status by supplying trace elements.
Who receives it
Adults · Children
Adult administration
To be used according to a physician's prescription, with plasma trace element levels checked to guide dosage adjustments. For patients receiving metabolically stable non-oral nutritional solutions: Zinc 2.5 to 4 mg daily, Copper 0.5 to 1.5 mg daily, Manganese 0.15 to 0.8 mg daily, Chromium 10 to 15 µg daily, Selenium 20 to 40 µg daily. For patients experiencing metabolically stable small intestine fluid losses: an additional 12.2 mg/L (amount of small intestine fluid loss) or 17.1 mg/kg.
Child administration
Pediatric patients - under 5 years: Zinc 100 µg per kg of body weight daily, Copper 20 µg per kg of body weight daily, Manganese 2 to 10 µg per kg of body weight daily, Chromium 0.14 to 0.20 µg per kg of body weight daily, Selenium 3 µg per kg of body weight daily.

Ingredients

Manufacturer
(주)오스코리아제약

Efficacy & effects

Improvement of nutritional status by supplying trace elements.

View approved original text

When trace elements such as zinc, copper, manganese, selenium, and chromium are supplied together during intravenous nutrition supplementation, essential minerals required by the body are provided, supporting overall metabolic function and the immune system. These trace elements participate in metabolism and various enzyme reactions, helping to prevent nutritional imbalances. Therefore, appropriate supplementation of trace elements during intravenous nutrition therapy plays a critical role in the patient's recovery and health improvement, enhancing the therapeutic effect.

How it is given

Adult administration

To be used according to a physician's prescription, with plasma trace element levels checked to guide dosage adjustments. For patients receiving metabolically stable non-oral nutritional solutions: Zinc 2.5 to 4 mg daily, Copper 0.5 to 1.5 mg daily, Manganese 0.15 to 0.8 mg daily, Chromium 10 to 15 µg daily, Selenium 20 to 40 µg daily. For patients experiencing metabolically stable small intestine fluid losses: an additional 12.2 mg/L (amount of small intestine fluid loss) or 17.1 mg/kg.

Child administration

Pediatric patients - under 5 years: Zinc 100 µg per kg of body weight daily, Copper 20 µg per kg of body weight daily, Manganese 2 to 10 µg per kg of body weight daily, Chromium 0.14 to 0.20 µg per kg of body weight daily, Selenium 3 µg per kg of body weight daily.

Precautions

This medication should not be used in premature infants and newborns due to the presence of benzyl alcohol, which can cause severe respiratory issues, especially in premature infants. When administering intravenously, it should be injected directly without dilution to prevent phlebitis, so it must be diluted before use. This medicine is a hypotonic solution and should only be used when mixed with other medications for injection. If any symptoms suggesting toxicity occur during administration, the use should be stopped immediately. Also, this medication contains aluminum, which poses a risk of toxicity for patients with impaired kidney function, especially when given for a long time to immature infants. Before injection, the physician must accurately assess the patient's condition and the required amount of trace elements, regularly checking the levels of trace elements in the blood to adjust dosages accordingly. Patients with renal failure should be cautious as zinc can accumulate in the body, and patients with biliary obstruction face risks of copper and manganese accumulation. Diabetic patients should also be careful as the chromium component can affect blood sugar control, necessitating confirmation of diabetes treatment. The safety of this medication has not been sufficiently established in pregnant women, so it should be used cautiously only when the therapeutic effect outweighs the risks. In cases of overdose, a variety of toxic symptoms may occur for each component such as zinc, copper, and selenium, so strict adherence to prescribed dosages is essential. If any toxic symptoms are suspected, immediate consultation with medical personnel is necessary. This medication must be used strictly according to a physician's prescription and handled carefully in a sterile condition. Before administration, ensure that the solution has not changed color or contains any foreign substances. During storage, keep the medication in a sealed container to avoid contact with air, maintaining a storage temperature between 15 to 30 degrees Celsius. This will safely preserve the medication's efficacy.

Side effects and when to seek care immediately

Serious side effects

  • Hypotension
  • pulmonary edema
  • jaundice
  • decreased urinary output
  • vascular congestion
  • hemorrhage/congestion/edema in the lungs
  • shock peripheral vascular collapse
  • coma.

Mild side effects

  • Sweating
  • blurred vision
  • tachycardia
  • significant hypothermia
  • diarrhea
  • vomiting
  • hair loss
  • brittle nails
  • dermatitis
  • dental damage
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  • gastrointestinal distress
  • irritability
  • depression
  • metallic taste
  • sweating
  • garlic smell during breathing
  • fatigue
  • behavioral changes
  • glare
  • peripheral edema
  • nausea
  • ulcers
  • kidney damage
  • liver damage
  • convulsions
  • coma.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication must be stored in a sealed container to avoid contact with air, and it is essential to maintain a storage temperature between 15 and 30 degrees Celsius. Proper storage ensures the medication's efficacy is safely preserved.

Appearance and packaging

Appearance

A colorless or slightly blue transparent liquid in a colorless transparent vial, injection solution.

Package unit

10 vials/box [10 mL/vial x 10]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.