Doneil 23 mg (Donepezil Hydrochloride Hydrate)

Adult dose

This drug is taken once daily just before bedtime, regardless of food intake. The initial recommended dose of Donepezil Hydrochloride is 5 mg once daily. For 4 to 6 weeks, 5 mg should be administered, after which the dosage may be increased to 10 mg based on clinical response evaluation. Patients who have taken 10 mg once daily for a minimum of 3 months may receive 23 mg once daily. It can be divided or crushed.

This medicine is used for the treatment of Alzheimer-type dementia symptoms with Donepezil Hydrochloride as its main ingredient. Do not take this drug if you are allergic to Donepezil Hydrochloride or any other components of this drug, or if you are pregnant or breastfeeding. In addition, individuals with lactose intolerance or specific genetic lactose degradation disorders should not take this medication. Patients with heart disease or conduction disorders should be cautious, as this drug can slow heart rate or cause arrhythmia. If you are taking non-steroidal anti-inflammatory drugs or have a history of peptic ulcers, this medication may exacerbate symptoms by promoting gastric acid secretion. Patients with a history of asthma or obstructive pulmonary disease should also use this drug cautiously as symptoms may worsen. This drug may affect the central nervous system, leading to various neuropsychiatric adverse reactions such as hallucinations, anxiety, insomnia, drowsiness, and dizziness. Digestive system reactions like nausea, vomiting, diarrhea, and loss of appetite are common, as well as reports of liver dysfunction and serious heart issues. During treatment, serious side effects like heart rhythm disturbances, myocardial infarction, hepatitis, cerebrovascular disorders, and extrapyramidal disorders may occur; consult medical personnel immediately if symptoms arise. This drug may interact with other medications, so caution is needed, especially with drugs affecting CYP3A4 or CYP2D6 enzymes, anticholinergic medications, antiarrhythmics, antidepressants, and antibiotics. Pregnant or breastfeeding women should generally avoid this medication, and if required, they must consult a doctor. The safety of this medication in children has not been established, so it should not be used in children. In case of overdose, serious symptoms such as nausea, vomiting, bradycardia, hypotension, and respiratory depression may arise; visit a hospital immediately for appropriate treatment. This drug should be kept out of the reach of children and stored in its original container to maintain quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, mouth/eye mucosal pain, shortness of breath or difficulty breathing, asthma attack, coughing with fever and respiratory abnormalities, yellowing of skin or eyes (jaundice), extreme lethargy, sudden severe headache, lightning headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• weakness
• dizziness
• insomnia
• hallucinations

This medication should be stored in a sealed container to prevent air or moisture infiltration. It is best stored at room temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

Red, bilaterally convex round film-coated tablets

Package unit

30 tablets/bottle