Esomezole Dials 40 mg (Esomeprazole Magnesium Trihydrate)

Adult dose

This medication can be taken without regard to meals. It should be swallowed with liquids such as water and must not be chewed or crushed. Patients who have difficulty swallowing capsules can open the capsule and mix the contents into half a cup of non-carbonated water for consumption. 1) Treatment of erosive esophagitis: Administer 40 mg once daily for 4 weeks. If symptoms persist or are not adequately treated, continue taking for an additional 4 weeks. 2) Prevention of recurrence in esophagitis patients: Administer based on the physician's direction.

Child dose

Adolescents aged 12 and over: For the treatment of erosive esophagitis, administer 40 mg once daily for 4 weeks. Children under 12 years: No experience in administration.

This medication should not be administered to patients who are allergic to this drug or its components, or who have had hypersensitivity reactions to benzimidazoles. Additionally, it should not be used in patients taking certain antiviral agents such as atazanavir, nelfinavir, and rilpivirine, or in women who are breastfeeding. This medication contains colorants, Yellow No. 5 and Red No. 40, thus patients with a history of allergies to these components should use it cautiously. While using this medication, various side effects such as blood-related abnormalities, allergic reactions, electrolyte imbalances, mental changes, headaches, dizziness, gastrointestinal problems, liver function abnormalities, and skin rashes may occasionally occur, and if symptoms arise, immediate consultation with a physician is necessary. Long-term use may cause hypomagnesemia, so it is important to regularly check magnesium levels in the blood. Furthermore, this medication suppresses gastric acid secretion, slightly increasing the risk of bacterial infections in the gastrointestinal tract; thus, if symptoms like diarrhea persist, a doctor should be informed. Long-term, high-dose use of this drug may increase the risk of fractures, so caution is necessary for patients at risk of osteoporosis. Data on the use of this medication during pregnancy is limited, so pregnant women should definitely consult a physician before use, and it is best for breastfeeding women to avoid this medication. In case of overdose, there is no specific antidote available, and symptomatic treatment is required. It should be stored out of the reach of children. This medication may interact with other drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist, especially when used in combination with antivirals, anticoagulants, antidepressants, and anticonvulsants. Lastly, this medication should only be used for the minimum necessary dosage and duration, and if there are changes in symptoms, consultation with a healthcare professional is essential.

Serious side effects

Hives, severe swelling (angioedema, facial swelling), chest tightness, difficulty breathing, anaphylactic reaction/shock, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome), acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), shortness of breath or trouble breathing, asthma.

Mild side effects

Headache, dizziness, drowsiness, insomnia, agitation, mental confusion, depression, aggression, hallucinations, taste disturbances, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distension, nausea, vomiting, dry mouth, stomatitis, gastrointestinal candidiasis, increased liver enzymes, hepatitis, dermatitis, itching, rash, hair loss, photosensitivity, fractures, joint pain, muscle pain, muscle weakness, fatigue, increased perspiration, Clostridium difficile-associated diarrhea, abdominal distention.

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. In addition, it is best to store the drug at room temperature between 1°C and 30°C. Storing it this way will help maintain its effectiveness for a longer period.

Appearance

A prolonged release hard capsule containing white or light yellow tablets and cloudy pink tablets, with a light pink upper and lower part.

Package unit

30 capsules/bottle, 30 capsules/box [(10 capsules/PTP x 3)], 100 capsules/bottle