Selenex Injection (Selenic Acid)

Adult dosage

For stable metabolic conditions during Total Parenteral Nutrition (TPN), inject 20 to 40 μg of selenium per day (this medication contains selenium 40 μg/mL). Monitor plasma selenium concentrations frequently for reference at the next dosing.

Children's dosage

Inject 3 μg per kg of body weight per day. Monitor plasma selenium concentrations frequently for reference at the next dosing.

This medication contains selenium and should not be used in patients with selenium toxicity. Excessive administration may result in toxicity; if any abnormal symptoms occur, use should be discontinued immediately. Direct infusion into peripheral veins may cause phlebitis; therefore, it must be diluted before use. As it is a storage solution, it must be administered after mixing with other solutions. Caution should be exercised in patients with impaired kidney function or premature neonates, as aluminium content may cause toxicity with long-term parenteral administration. While administering this medication, pain or allergic reactions may occur very rarely; if such symptoms arise, consult a physician or pharmacist immediately. Discontinue use and consult a professional if symptoms such as dermatitis, foul odor when sweating or breathing, hair loss, restlessness, vomiting, etc., appear. Before administration, ensure to check for precipitation or discoloration visually, and prepare under aseptic conditions. Adjust the selenium dosage in cases of impaired kidney or gastrointestinal function. In transfusion patients, consider the selenium dosage and continuously monitor serum concentrations. In pregnant women or those who may become pregnant, consider the effects on the fetus for careful administration, as there may be risks of fetal malformations. For nursing mothers, safety has not been established, so breastfeeding should be discontinued or the medication dosage should be adjusted. In cases of overdose, effects may include disruption in nail and hair growth, dermatitis, oral abnormalities, gastrointestinal issues, tension, depression, metallic taste, vomiting, and garlic-like odor from the mouth. In severe cases, fatal symptoms such as vascular collapse, pulmonary hemorrhage, and gastric mucosal damage may occur, requiring immediate treatment. In cases of overdose, gastric lavage, diuresis, and high-dose vitamin C administration may be necessary, and in extreme overdose cases, dialysis may be needed. This medication should be kept out of reach of children and stored in a dry place at room temperature in its original packaging. It should be used immediately after opening, and transferring it to another container is not advisable for quality maintenance.

Serious side effects

Allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, etc.), acute peripheral vascular collapse, internal vascular congestion, pulmonary hemorrhage, congestion, and edema (difficulty breathing or shortness of breath), gastric mucosal erythema, symptoms of acute overdose that can be fatal.

Mild side effects

• Pain
• dermatitis
• foul odor when sweating or breathing
• hair loss
• restlessness
• vomiting
• oral abnormalities
• gastrointestinal issues
• tension
• depression

This medication should be stored in a sealed container to prevent air from entering and kept in a cool place between 15 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy over a longer period.

Appearance

A colorless and odorless transparent liquid in a colorless and transparent vial.

Package unit

For domestic use - 10 milliliters/vial [10 mL x 10 vials]