Medication info

Halim Zinc Injection (Zinc Sulfate Hydrate)

Prescription medicationInjections
Ingredient · strength
Zinc Sulfate Hydrate›4.4mg / 1mL
Manufacturer / importer
한림제약(주)
Appearance
A colorless, odorless, transparent liquid in a colorless, transparent vial injection.
Packaging
10mL X 10 vials
Approval status
Active

MFDS item code 202006277 · Notified 2020.09.11

Summary

Main use
Prevention of zinc deficiency and improvement of nutritional status
Who uses it
Adults · Children
Adult dosage
For metabolically stable TPN patients, the dosage is 2.5 to 4 mg/day. For adult patients with fluid loss in the small intestine, an additional 12.2 mg/L (amount of fluid loss) or an additional 17.1 mg/kg (amount of excretion) should be administered. For acute burn conditions, the dosage is 4.5 to 6 mg/day. Use as prescribed by a physician, and adjust the dosage based on plasma trace element levels.
Children's dosage
Children under 5 years of age should take 100 ug/kg/day. Premature infants weighing 3 kg or less should take 300 ug/kg/day.

Ingredients

Manufacturer
한림제약(주)

Efficacy & effects

Prevention of zinc deficiency and improvement of nutritional status

View approved original text

Zinc can become deficient during total parenteral nutrition (TPN), making it important to provide appropriate supplementation. Zinc is an essential mineral for maintaining immune function and wound healing, with deficiency potentially leading to various complications. Therefore, zinc supplementation helps to improve nutritional status and maintain health in patients receiving TPN.

Dosage and Administration

Adult dosage

For metabolically stable TPN patients, the dosage is 2.5 to 4 mg/day. For adult patients with fluid loss in the small intestine, an additional 12.2 mg/L (amount of fluid loss) or an additional 17.1 mg/kg (amount of excretion) should be administered. For acute burn conditions, the dosage is 4.5 to 6 mg/day. Use as prescribed by a physician, and adjust the dosage based on plasma trace element levels.

Children's dosage

Children under 5 years of age should take 100 ug/kg/day. Premature infants weighing 3 kg or less should take 300 ug/kg/day.

Precautions

This medication should not be injected directly into the peripheral vein without dilution. The reason is that direct injection may cause inflammation in the vein or potentially harm the kidneys with excess zinc. The amount of zinc included in this medication is very low, so toxic symptoms are generally rare. When mixing this drug with TPN solutions, it is recommended to work in a place with special equipment to maintain sterility. Before injection, the medication should be visually checked for any precipitate or discoloration. Zinc administration may reduce copper levels, so it is necessary to periodically check blood levels of copper and zinc. This drug is primarily excreted through the intestines and kidneys; therefore, caution is needed in patients with poor excretory function, as zinc may accumulate in the body. This medication should be used during pregnancy or in women of childbearing potential only when the therapeutic benefits outweigh the risks. Zinc can cross the placenta and be transferred to the fetus, and it may also be present in breast milk. In cases of overdose, symptoms such as nausea, vomiting, dehydration, electrolyte imbalance, dizziness, abdominal pain, drowsiness, and coordination disorders may occur. Calcium intake may help prevent toxicity due to excess zinc. This medication should be kept out of reach of children and stored in a dry place at room temperature within sealed packaging. Since it does not contain preservatives, any unused medication should be discarded.

Side effects and when to seek care immediately

Mild side effects

  • Nausea
  • vomiting
  • dehydration
  • electrolyte imbalance
  • dizziness
  • abdominal pain
  • drowsiness
  • coordination disorders

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent exposure to air, and it is safe to store at room temperature between 1 to 30 degrees Celsius. Therefore, it is advisable to keep it in a cool, dry place until use.

Appearance and packaging

Appearance

A colorless, odorless, transparent liquid in a colorless, transparent vial injection.

Package unit

10mL X 10 vials

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.