Medication info
Diethyl Tablet (Diethylpropion Hydrochloride)

Diethyl Tablet (Diethylpropion Hydrochloride)

Prescription medicationTablet
Ingredient · strength
Diethylpropion Hydrochloride›25mg / 1 tablet
Manufacturer / importer
Intro Biopharma Co., Ltd.
Appearance
White to pale yellow rectangular tablet
Packaging
Bottle packaging - 30 tablets/bottle, Bottle packaging - 300 tablets/bottle
Approval status
Active

MFDS item code 202006161 · Approved 2020.09.03

Summary

Main use
Short-term adjunctive treatment for weight loss in patients with obesity
Who uses it
Adults
Adult dosage
Adults: Administer 25 mg of diethylpropion hydrochloride orally 3 times daily, 1 hour before meals. The maximum daily dose is 75 mg, and the last dose should be taken no later than 4 hours before bedtime. To minimize the potential for abuse, prescribe or dispense the lowest possible dose during the initial period (within 2 weeks), adjusting the dose individually to achieve an adequate response. This medication should be administered for a short period (within 4 weeks). However, to reduce the risk of inappropriate use of this medication, treatment may be continued if the patient achieves satisfactory weight loss within the first 4 weeks (at least 1.8 kg of weight loss, or weight loss considered satisfactory by both the physician and the patient).

Ingredients

Manufacturer
Intro Biopharma Co., Ltd.

Efficacy & effects

Short-term adjunctive treatment for weight loss in patients with obesity

  • Obesity
View approved original text

This medication is used as a short-term adjunctive treatment for weight loss in patients with a body mass index (BMI) of 30 or higher, or in patients with a BMI of 27 or higher with accompanying risk factors such as hypertension, diabetes, and hyperlipidemia, who have not responded to appropriate dietary measures or exercise. It should be used alone and not in combination with other appetite suppressants. BMI is used as an indicator to assess the degree of obesity by calculating weight (kg) divided by height (m) squared. This medication is used to effectively assist in weight loss and improve health risks associated with obesity.

Dosage and Administration

Adult dosage

Adults: Administer 25 mg of diethylpropion hydrochloride orally 3 times daily, 1 hour before meals. The maximum daily dose is 75 mg, and the last dose should be taken no later than 4 hours before bedtime. To minimize the potential for abuse, prescribe or dispense the lowest possible dose during the initial period (within 2 weeks), adjusting the dose individually to achieve an adequate response. This medication should be administered for a short period (within 4 weeks). However, to reduce the risk of inappropriate use of this medication, treatment may be continued if the patient achieves satisfactory weight loss within the first 4 weeks (at least 1.8 kg of weight loss, or weight loss considered satisfactory by both the physician and the patient).

Precautions

This medication must not be used in conjunction with other appetite suppressants and should be used alone for a short duration only. Combining this medication with other drugs for weight loss is not recommended due to the lack of established safety and efficacy. This medication should be prescribed strictly as its weight loss effect may not be significant even when used with dietary measures. Long-term use may lead to drug abuse and dependency, therefore careful usage is required. If signs of mental dependence appear, the dosage should be gradually reduced, and sudden discontinuation should be avoided as it could trigger symptoms such as fatigue and depression. If angina, fainting, peripheral edema, or exercise-induced breathing difficulties occur, use should be discontinued immediately and pulmonary arterial hypertension should be checked. There is a potential risk of serious cardiovascular adverse reactions such as pulmonary arterial hypertension and valvular heart disease, so cardiac testing may be required before treatment. This medication should not be administered to patients with certain diseases or conditions (e.g., hypertension, glaucoma, hyperthyroidism, heart disease, depression, etc.). Patients with mild cardiovascular diseases or hypertension should have their blood pressure and cardiovascular status monitored regularly during administration. Patients with epilepsy should be closely observed for seizure occurrences and may require dosage adjustments as needed. Common side effects include insomnia, irritability, dizziness, anxiety, restlessness, dry mouth, epigastric pain, palpitations, elevated blood pressure, ECG changes, movement disorders, blurred vision, hyperactivity, restlessness, unusual euphoria, discomfort, and sometimes depression, tremors, dilated pupils, drowsiness, fatigue, headache, diarrhea, constipation, nausea, vomiting, abdominal discomfort, unpleasant taste, xerostomia, stomatitis, and other gastrointestinal disturbances, erectile dysfunction, dysmenorrhea, changes in sexual desire, menstrual disorders, and gynecomastia. This medication affects the central nervous system, so caution is advised for individuals driving or operating hazardous machinery. This medication may interact with other medications, so it is crucial to consult with healthcare professionals regarding other medications being taken. Women who are pregnant or breastfeeding are advised not to use this medication, and women who could become pregnant should also use caution. Children under the age of 16 should not use this medication, and elderly patients should avoid use due to potential renal function decline. In case of overdose, symptoms of toxicity and serious side effects may occur, necessitating immediate medical attention for detoxification and symptomatic treatment. This medication should be kept out of reach of children and stored in a tightly sealed container.

Side effects

Insomnia, irritability, dizziness, anxiety, restlessness, dry mouth, tachycardia, epigastric pain, arrhythmia, palpitations, increased blood pressure, changes in electrocardiogram, primary pulmonary hypertension, valvular heart disease, movement disorders, blurred vision, hyperexcitability, agitation, abnormal euphoria, discomfort, depression, tremor, dilated pupils, drowsiness, lethargy, headache, cerebrovascular accident, psychotic episodes, increased seizure disorders, diarrhea, constipation, nausea, vomiting, abdominal discomfort, abdominal pain, unpleasant taste, xerostomia, stomatitis, urticaria, rash, petechiae, erythema, erectile dysfunction, dysmenorrhea, changes in libido, menstrual pain, gynecomastia, bone marrow suppression, leukopenia, agranulocytosis, thrombocytopenia, shortness of breath, hair loss, myalgia, urination disorders, polyuria, sweating, angioedema, agitation, tremor, hyperreflexia, hypersensitivity, rapid breathing, confusion, aggression, hallucinations, panic state, frequent seizures, exhaustion due to central nervous system stimulation, drowsiness, fatigue, coma, changes in blood pressure, circulatory collapse, nausea, vomiting, diarrhea, abdominal cramping, severe skin disease, hyperfunction, personality change, schizophrenia-like mental disorders

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Moreover, to maintain the effectiveness of the medication, it is advisable to store it at room temperature between 1°C and 30°C.

Appearance and packaging

Appearance

White to pale yellow rectangular tablet

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 300 tablets/bottle

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Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.