Janugreen Tablets 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

For monotherapy or combination therapy, the recommended dose is 100 mg once daily, with a maximum daily dose of 100 mg. In patients with kidney impairment, dosage adjustment may be necessary based on kidney function. - Mild kidney impairment (eGFR 60-90 mL/min/1.73 m2): No dosage adjustment required - Moderate kidney impairment (eGFR 45-60 mL/min/1.73 m2): No dosage adjustment required - Moderate kidney impairment (eGFR 30-45 mL/min/1.73 m2):

This drug may cause serious allergic reactions during use, so symptoms such as rash or difficulty breathing must be reported to healthcare professionals immediately. Serious inflammation of the pancreas (pancreatitis) may occur, so if symptoms like abdominal pain or vomiting arise, consultation with a physician is essential. This drug should not be used in patients with type 1 diabetes or diabetic ketoacidosis. Patients with reduced kidney function may need to adjust the dosage of this drug, and regular kidney function testing is important. When used in conjunction with other blood sugar-lowering agents, the risk of hypoglycemia may increase, so blood sugar levels should be monitored frequently and medication dosages adjusted as necessary. If severe joint pain or skin blistering occurs, the use of this drug should be stopped immediately, and a physician should be consulted. It is not recommended for use in pregnant or breastfeeding women, and safety in children and adolescents under 18 years of age has not been established. In case of overdose, immediate hospital visit for appropriate treatment is necessary; some may be removed through hemodialysis. Regular health assessments, including liver function and blood tests, during treatment with this drug are advisable.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, exfoliative skin disorders including Stevens-Johnson syndrome, acute pancreatitis, acute renal failure, severe and disabling joint pain, bullous pemphigoid, cardiac arrest

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• abdominal pain
• nausea
• diarrhea
• constipation
• vomiting
• muscle pain
• limb pain

Store this drug in a tightly sealed container to prevent air or moisture from entering, and keep it at room temperature between 1 and 30 degrees Celsius. This will help maintain its effectiveness over time.

Appearance

Light orange, round, biconvex film-coated tablets

Package unit

30 tablets per box [10 tablets/PTP×3]