Janugreen 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg either as monotherapy or combined therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustment is necessary according to renal function. - Mild renal impairment (eGFR 60 to < 90) does not require dosage adjustment. - Moderate renal impairment (eGFR 45 to < 60) does not require dosage adjustment. -

This medication may cause severe allergic reactions after administration, so if symptoms such as skin rash or difficulty breathing occur, it should be discontinued immediately and a doctor consulted. During the use of this medication, serious pancreatic inflammation called pancreatitis may occur, so should severe abdominal pain or vomiting arise, immediate medical attention should be sought. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor should it be administered to those with allergies to this medication or its components. Patients with impaired kidney function should have their dosage adjusted, and regular kidney function tests should be conducted according to the doctor's instructions. Colds and flu-like symptoms, headache, dyspepsia, diarrhea, nausea, etc., may occur during the use of this medication; if symptoms are severe, consulting healthcare professionals is advisable. When taken with insulin or sulfonylureas, the risk of hypoglycemia may increase, so blood sugar levels should be monitored frequently and should hypoglycemic symptoms occur, immediate action should be taken. If severe joint pain or blistering symptoms appear, the use of this medication should be stopped and a specialist should be consulted. Pregnant or breastfeeding women are advised to avoid this medication, and the safety and efficacy in children and adolescents under 18 have not been established. Elderly patients may experience decreased kidney function; therefore, regular kidney function tests before and after administration are needed, and dosage adjustment may be required. In case of overdose, immediate medical attention should be sought for appropriate treatment, and some of the drug may be removed through dialysis. This medication has relatively few drug interactions, but it is important to inform healthcare providers of any medications being taken, particularly when taken with immunosuppressants or cardiovascular drugs.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• acute pancreatitis
• acute renal failure
• severe and disabling joint pain
• bullous pemphigoid
• pneumonia
• diabetic complications

Mild side effects

• Headache
• upper respiratory infection
• nasopharyngitis
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a sealed container to prevent air exposure, at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's efficacy.

Appearance

Pink round biconvex film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP×3]