Celsita Tablet 25mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

The usual dose of this medication is 100mg once daily, either as monotherapy or in combination therapy, with a maximum daily dose of 100mg. In patients with renal impairment, in cases of moderate renal impairment (glomerular filtration rate [eGFR] 30–45 mL/min/1.73 m²), 50mg is administered once daily. In severe renal impairment (glomerular filtration rate [eGFR] 15–30 mL/min/1.73 m²) or in terminal renal failure patients (glomerular filtration rate [eGFR]

This medication may cause allergic reactions; therefore, if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a doctor. While taking this medication, severe inflammation of the pancreas known as acute pancreatitis may occur; if symptoms such as abdominal pain or vomiting arise, notify healthcare professionals promptly. Patients with type 1 diabetes or diabetic ketoacidotic conditions should not take this medication, and those with allergies to this medication or its components should also avoid use. Patients with reduced kidney function need to adjust the dosage of this medication, so consult with a doctor to determine the appropriate dosage based on kidney status. This medication may induce hypoglycemia, especially when taken with insulin or sulfonylureas, so regularly monitor blood sugar levels and be aware of symptoms of hypoglycemia. Severe joint pain may occur, so if severe pain persists, inform a doctor to receive appropriate measures. If there are blisters or inflammation on the skin, discontinue use of this medication immediately and consult a dermatologist. Pregnant or breastfeeding women should preferably avoid using this medication, and safety has not been established for children and adolescents under 18 years of age. Elderly patients may experience reduced kidney function, necessitating dosage adjustments and regular kidney function monitoring. In case of overdose, remove the medication from the gastrointestinal tract and closely observe the condition including the electrocardiogram; consider blood dialysis if necessary. This medication may interact with some drugs, so if other medications are being taken, it is essential to inform a doctor or pharmacist.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, Stevens-Johnson syndrome and exfoliative skin disease (severe skin adverse reaction), acute pancreatitis, acute renal failure, pneumonia, cardiac arrest, severe hypoglycemia, severe joint pain with disability, bullous pemphigoid, liver dysfunction (elevation of liver enzymes, potential for jaundice), acute pancreatitis, worsening kidney function

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• muscle pain
• limb pain

Store this medication in a tightly sealed container to prevent air exposure and keep it at a temperature between 1 and 30 degrees Celsius. This helps maintain the effectiveness of the medication for a longer period.

Appearance

Light orange, round, double convex, film-coated tablet

Package unit

28 tablets (14 tablets/PTP x 2) 28 tablets - 14 tablets/PTP [28 tablets (14 tablets/PTP x 2)] 30 tablets - 10 tablets/PTP [30 tablets (10 tablets/PTP x 3)]