Sitarren Tablet 25 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, either alone or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dose adjustment is required based on renal function. - Mild renal impairment (glomerular filtration rate 60-90 mL/min/1.73 m2) does not require dose adjustment. - Moderate renal impairment (glomerular filtration rate 45-60 mL/min/1.73 m2) requires careful monitoring.

This medication may cause serious allergic reactions rarely, so if symptoms such as skin rash or difficulty breathing occur within 3 months after administration, discontinue use immediately and consult a doctor. This medication poses a risk of pancreatitis, which is inflammation of the pancreas, so if symptoms such as abdominal pain, nausea, or vomiting occur, prompt medical evaluation is necessary. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in cases of allergy to this medication or its ingredients. Patients with impaired renal function need dose adjustment, so regular renal function tests should be performed, and it should be taken according to a doctor’s instructions. This medication may cause side effects including headache, upper respiratory infection, nasopharyngitis, diarrhea, nausea, constipation, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, dyspepsia, dizziness, increased triglycerides, increased low-density lipoproteins, hyperglycemia, hypertension, weight loss, and erectile dysfunction whether used alone or in combination with other diabetes medications; persistent symptoms should be reported to medical professionals. If taken with insulin or sulfonylureas, the risk of hypoglycemia may increase, necessitating periodic blood sugar checks and immediate action if hypoglycemic symptoms arise. If severe joint pain or symptoms such as blisters occur during medication use, notify a doctor promptly and discontinue use. This medication is not recommended for women during pregnancy or breastfeeding, so it is essential to consult with healthcare professionals if applicable. Elderly patients may experience reduced renal function, thus requiring dose adjustments and regular renal function tests. In case of overdose, immediate medical attention is needed for appropriate treatment, and this medication can be partially removed through hemodialysis. This medication has low potential for drug interactions, but it should be disclosed to healthcare professionals when taking specific medications.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe skin reactions (rash, Stevens-Johnson syndrome, exfoliative skin diseases), acute pancreatitis, difficulty breathing (respiratory issues), liver abnormalities (elevated liver enzymes, jaundice), severe joint pain accompanied by disability, blistering similar to pemphigus, severe cardiovascular events (including cardiac arrest), acute renal failure, severe hypoglycemia, severe edema with increased blood pressure, severe allergy

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• muscle pain
• limb pain
• back pain

Store this medication in a tightly sealed container protected from air exposure, ideally at room temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the efficacy of the medication.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

30 tablets/box [(10 tablets/PTP x 3)]