Ursodeoxycholic Acid 300 mg Tablets

Adult dose

For improvement of liver function in primary biliary cirrhosis, ursodeoxycholic acid is administered orally as 300 mg three times a day with meals. For prevention of gallstones in patients with rapid weight loss, 300 mg is taken twice a day. For gastric cancer patients who have undergone gastrectomy, 300 mg is taken once a day.

This medication is used for the prevention or treatment of gallstones. Firstly, this medication should not be used in certain patients. For example, individuals who are allergic to the ingredients of this medication or bile acids, those with severely obstructed bile ducts, acute hepatitis patients, individuals with certain types of gallstones, patients without a functioning gallbladder, those with severe cholecystitis or cholangitis, pregnant or nursing women, children, kidney disease patients, and individuals with inflammation in the stomach or intestines should not take this medication. Additionally, patients with severe pancreatic diseases or gallstones in the bile ducts, and those with very poor liver function should exercise greater caution when taking this medication. Taking this medication may occasionally cause gastrointestinal and skin symptoms such as diarrhea, nausea, vomiting, abdominal pain, constipation, heartburn, itching, and rash. Rarely, serious side effects such as interstitial pneumonia, liver function abnormalities, and leukopenia may occur, so if symptoms worsen, immediate consultation with medical personnel is necessary. While taking this medication, regular liver function tests and blood tests should be done, and overdose typically presents with diarrhea, so treatment corresponding to symptoms is needed. This medication can enhance the effects of certain diabetes medications, and when taken with antacids or certain lipid-lowering medications, it may interfere with the absorption of this medication. It is also advisable not to take it with medications that may cause liver damage. It is safest for pregnant women and nursing mothers not to take this medication, and for children, the safety and efficacy of this medication have not been established, hence it is not used. Elderly individuals require special care, and this medication should be stored out of reach of children.

Serious side effects

Interstitial pneumonia (fever, cough, difficulty breathing, abnormal chest X-ray), elevated serum bilirubin levels (suspected symptoms of jaundice), potential worsening of jaundice in advanced cirrhosis

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal pain
• constipation
• heartburn
• discomfort in the upper abdomen
• itching
• rash
• general fatigue

This medication may be sensitive to air and moisture, so it should be stored in a tightly sealed container. Moreover, avoid storing it in excessively hot or cold locations and keep it at room temperature between 1 and 30 degrees Celsius.

Appearance

White round tablets

Package unit

Bottle packaging - 30 tablets/bottle, Bottle packaging - 300 tablets/bottle, PTP packaging - 100 tablets/box [10 tablets/PTP x 10]