Terracoxen Soft Capsule (Naproxen)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Administer 250~500mg of naproxen orally twice a day (every 12 hours). 2. Acute gout: Administer 750mg as a loading dose orally and then 250mg every 8 hours until the attack subsides. 3. Skeletal muscle disorders, post-surgical pain, pain after tooth extraction, dysmenorrhea, tendinitis, bursitis: Administer 500mg as a loading dose orally and then 250mg every 6~8 hours. Do not exceed a total daily dose of 1250mg. 4. Migraine: Administer 750mg of naproxen as a loading dose orally. If necessary, an additional 250-500mg may be taken throughout the day; doses can be taken 30 minutes after the initial doses. Do not exceed a total daily dose of 1250mg. Adjust dosage as appropriate based on age and symptoms.

This medicine may cause gastrointestinal bleeding if taken by individuals who regularly consume more than three drinks a day; it is essential to consult with a doctor or pharmacist. This medicine can affect the cardiovascular system, hence patients with cardiovascular diseases or risk factors must be cautious, as serious issues like myocardial infarction or stroke may occur. Serious adverse reactions such as gastrointestinal bleeding, ulcers, and perforation may occur, especially in the elderly, so immediate consultation with medical personnel is necessary if symptoms arise. Patients with peptic ulcers, severe blood disorders, liver impairment, heart failure, kidney disorders, hypertension, or those allergic to any ingredient of this medication should not take it. Various side effects such as hypersensitivity, gastrointestinal issues, blood disorders, liver impairment, kidney disorders, neuropsychiatric issues, and skin rashes may occur, and immediate cessation of use and consultation with healthcare providers is advised in case of abnormal symptoms. This medicine may interact with other non-steroidal anti-inflammatory drugs or specific medications, so caution is required when taken concomitantly. It should be avoided during pregnancy, especially in the later stages, as it may be harmful to the fetus, and for breastfeeding mothers as it may affect the baby. Children and the elderly are at a higher risk for adverse reactions, so they should be administered the minimum effective dose cautiously, with regular monitoring required. Overdose may cause symptoms such as drowsiness, indigestion, vomiting, necessitating immediate medical attention.

Serious side effects

• Hives
• severe swelling
• chest tightness
• difficulty breathing
• cold sweat
• pallor
• hematemesis
• gastrointestinal bleeding
• peptic ulcers
• perforations

Mild side effects

• Nausea
• abdominal pain
• vomiting
• loss of appetite
• dyspepsia
• heartburn
• diarrhea
• constipation
• stomatitis
• abdominal bloating

Drug interactions

Do not take this medicine with other non-steroidal anti-inflammatory drugs and naproxen derivatives. Phenytoin-class anticonvulsants, sulfa drugs, sulfonylurea-class hypoglycemic agents, propranolol and other beta-blockers, ACE inhibitors (e.g., captopril), loop and thiazide diuretics, probeneic, aspirin, lithium, methotrexate, cumarins (e.g., warfarin), zidovudine, and fluoroquinolone antibiotics (e.g., enoxacin) may interact.

This medicine may be sensitive to air or moisture, so it must be kept in a tightly sealed container. It is advisable to store it at room temperature between 1 to 30 degrees Celsius. Proper storage is essential to maintain the effectiveness of the medication.

Appearance

Transparent teal oval soft capsule containing a colorless clear liquid

Package unit

10 capsules/PTP