Sitacan Tablet 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, whether as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments are necessary depending on their kidney function. - Mild (glomerular filtration rate eGFR ≥ 60 and < 90 mL/min/1.73 m2): No dosage adjustment necessary. - Moderate (glomerular filtration rate eGFR ≥ 45 and < 60 mL/min/1.73 m2): Dosage adjustment required.

This medication may cause serious allergic reactions in some patients, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, immediately discontinue use and consult a healthcare professional. This medication can induce a condition called pancreatitis, which is inflammation of the pancreas; therefore, if symptoms like abdominal pain, nausea, or vomiting occur, immediate medical attention is required. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should not be given to patients with allergies to its components. Patients with impaired renal function must adjust the dosage of this medication; regular kidney function tests should be performed and it's essential to take this medication as directed by a healthcare professional. While taking this medication, symptoms of hypoglycemia may occur, so blood sugar levels should be closely monitored, especially when used with insulin or sulfonylurea drugs. If severe joint pain or blistering skin symptoms appear, immediately discontinue use and consult a healthcare professional. Use of this medication during pregnancy or breastfeeding is not recommended, and safety and efficacy have not been established for children and adolescents under 18 years of age. Elderly patients may have reduced kidney function, so it is important to regularly assess kidney function before and after taking this medication. In the event of overdose, general emergency measures should be taken, and blood dialysis may be necessary to remove the medication. No significant interactions have been reported with this medication when taken with other specific drugs; however, caution is needed with medications such as digoxin, so it is crucial to inform the healthcare professional about all medications being taken. If any abnormal symptoms occur while taking this medication, it is vital to consult a healthcare professional immediately to receive appropriate measures.

Serious side effects

Severe hypersensitivity reactions (anaphylaxis, angioedema, urticaria), severe skin reactions (Stevens-Johnson syndrome, rash, blistering dermatitis), acute pancreatitis, acute renal failure, severe edema (peripheral edema), severe and disabling arthralgia, rhabdomyolysis, jaundice, severe neurological symptoms (cardiac arrest), pneumonia, diabetes complications, metabolic acidosis, cardiac arrest

Mild side effects

• Upper respiratory tract infection
• nasopharyngitis
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly closed, airtight container and kept at room temperature between 1 to 30 degrees Celsius. This storage method helps maintain the effectiveness of the medication for a longer period.

Appearance

Pale yellow-pink, round, biconvex film-coated tablet

Package unit

30 tablets/PTP [10 tablets/PTP X3]