Sitagliptin Tablet 100mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The usual dosage is 100 mg once daily, whether as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. In patients with renal impairment, dose adjustments are necessary based on renal function. - Mild renal impairment (eGFR ≥ 60 and < 90 mL/min/1.73 m²): No dose adjustment required - Moderate renal impairment (eGFR ≥ 45 and < 60 mL/min/1.73 m²):

This medication may cause severe allergic reactions; if symptoms such as skin rash or difficulty breathing occur, stop taking the medication immediately and consult a physician. While taking this medication, acute pancreatitis can occur, a serious inflammation of the pancreas, so immediate medical attention is required if symptoms like abdominal pain or vomiting develop. This medication should not be used in patients with type 1 diabetes or those with diabetic ketoacidosis, nor in patients who are allergic to this medication or its components. Patients with impaired renal function require dose adjustments, so renal function tests should be performed regularly and the medication should be taken under the guidance of a physician. This medication lowers blood sugar levels, therefore caution is advised as hypoglycemia may occur if taken with other hypoglycemic agents such as insulin or sulfonylurea. Severe joint pain or skin blistering may occur, so notify a physician immediately if these symptoms present. The use of this medication is not recommended for women who are pregnant or breastfeeding, and safety and efficacy have not been established for children or adolescents under 18 years. Elderly patients may commonly experience impaired renal function, so monitoring of renal function before and during therapy is important. In case of overdose, general symptomatic treatment is recommended, and if necessary, blood dialysis may be used to remove some of the medication. This medication has relatively few significant interactions with other drugs, but patients should always consult a physician or pharmacist when taking specific medications. If any unusual symptoms or discomfort arise while taking this medication, consult medical personnel immediately.

Serious side effects

Hives, severe swelling (edema), anaphylaxis, angioedema, severe allergic reactions, exfoliative skin disease, Stevens-Johnson syndrome, severe rash with fever, blistering, skin peeling, oral/ocular mucosal pain, acute pancreatitis, difficulty breathing, jaundice, sudden and severe headache, seizures, altered consciousness, significant reduction in urine output, severe edema associated with high blood pressure, serious hypoglycemia, acute renal failure, severe conditions and disability

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly closed container to prevent air infiltration and kept at room temperature between 1 and 30 degrees. Proper storage will help maintain the medication's effectiveness.

Appearance

Pale orange, round, biconvex, film-coated tablet

Package unit

30 tablets/PTP [10 tablets/PTP x3]