Xone A Tablet 5/160/10 mg

Adult dose

The recommended dosage is one tablet once daily with water. It is recommended to take it at the same time each day (e.g., in the morning) if possible. The dosing of amlodipine/valsartan combination and atorvastatin should be individualized for each patient. The dosage for the amlodipine/valsartan combination is as follows: - 5/80 mg: To patients whose blood pressure is not adequately controlled with amlodipine 5 mg or valsartan 80 mg monotherapy.

This drug can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. If there is suspicion of a muscle-related disease or if there is a significant increase in creatine kinase levels, the use of this drug should be discontinued, and caution is needed in patients at risk of severe myopathy or rhabdomyolysis. Patients allergic to any ingredients in this drug or having severe liver or kidney disease should not take it. Pregnant or nursing women should avoid its use. Patients with low sodium or fluid levels, patients with hyperkalemia, and patients with renal artery stenosis should carefully check their conditions and be closely monitored before taking this drug. Care should be taken when this drug is used in patients with heart conditions such as heart failure, post-myocardial infarction patients, or aortic stenosis. This drug can interact with various medications, so patients taking other medications must inform their doctor or pharmacist, especially when using it in combination with certain antibiotics, antifungals, or immunosuppressants. Patients may experience dizziness or fatigue when driving or operating machinery; therefore, caution is advised. If symptoms like muscle pain, weakness, or fever occur while taking this drug, the medical staff should be notified immediately, and if there are signs of liver dysfunction or suspected allergic reactions, it should be discontinued and medical advice sought. Women of childbearing potential should use appropriate contraception to avoid pregnancy during this medication period, and nursing mothers are advised to avoid taking this drug. The safety of this medication in children has not been established; therefore, it is preferable not to use it in pediatric patients.

Serious side effects

Hives, severe swelling (edema), angioedema, anaphylactic edema, chest tightness, difficulty breathing, shortness of breath, asthma attacks, pallor, cold sweat, severe rash with fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, significant reduction in urine output

Mild side effects

Eye abnormalities (dry eyes, visual disturbances, double vision, blurred vision), nausea, headache, dizziness, drowsiness, sensory disturbances, vertigo, tinnitus, tachycardia, palpitations, syncope, orthostatic hypotension, hypotension, cough, throat and laryngeal pain, diarrhea, abdominal pain, constipation, dry mouth, rash, erythema, sweating, itching, muscle cramps, weakness, joint swelling, back pain, arthritis, frequent urination, polyuria, erectile dysfunction, edema, facial swelling, peripheral edema

This drug may be sensitive to air or moisture, so it should be stored in a well-closed container. It is best to maintain room temperature between 1 degree and 30 degrees. This will help maintain the drug's effectiveness for a long time.

Appearance

Pale yellowish-brown oval film-coated tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle